Syllabus
Introduction to forensic and clinical toxicology. Disposition of xenobiotics in organism.
Biotransformation. Industrials, pharmaceuticals, illicit drugs, toxic effects.
Systematic toxicological analysis for unknown drug. Screening and confirmation.
Preliminary immunochemical detection. Chromatographical methods in toxicology.
Principles of mass spectrometry and its significance for identification of unknown poison in a trace toxicological analysis. Development and validation of toxicological methods.
Alternative biological matrices and their significance in toxicology. Drugs of abuse, legislation.
Drugs and driving. Interpretation of toxicological findings.
Interesting case reports.
Annotation
Analytical toxicology in present. Disposition and metabolism of toxic substances, pharmacokinetics, pharmacodynamics, toxic effects. Differencial diagnostics of intoxications. Systematic toxicological analysis.
Screening and confirmation. Development of new methods.
Drugs of abuse. Legislation in toxicology.
Drugs and driving. Interpretation of toxicological findings.
Interesting case reports.