Sylabus
The lectures take place each Wednesday and Friday at The Dept. of Stomatology Lecture Hall, Kateřinská 32, Praha 2,3rd. floor: 1 3rd October 10:45-12:15 Prof. V.Kožich Introduction to biochemical genetics 2 5th October 10:45-12:15 Prof.
V.Kožich Hereditary disorders of amino-acid metabolism 3 10th October 10:45-12:15 Dr. M.Hřebíček Disorders of mitochondrial metabolism 4 12th October 10:45-12:15 Dr.
M.Hřebíček Hereditary disorders of metabolism and biogenesis of lysosomes and peroxisomes 5 17th October 10:45-12:15 Dr. M.Hřebíček Disorders of purine and pyrimidine metabolism and porphyrias; pathobiochemistry of fasting 6 19th October 10:45-12:15 Dr.M.Hřebíček Hereditary disorders of saccharide metabolism and protein glycosylation 7 24th October 10:45-12:15 Prof.
V.Kožich Diagnosis and therapy of monogenic disorders of metabolism 8 26th October 10:45-12:15 Doc. J.Křemen Mechanisms of tumour disease formation (physical, chemical and viral carcinogenesis) 9 31st.
October 10:45-12:15 Doc. Z.
Kleibl Pathobiochemistry of tumorigenesis (pathobiochemistry of malignant transformation) 10 2.nd November 10:45-12:15 Dr. M.Zikán Principles of cancer progression (regulation of angiogenesis, formation of metastases) 11 7th November 10:45-12:15 Prof.
A. Šedo Signal transduction elements as therapeutic targets 12 9th November 10:45-12:15 Doc. P.Pohlreich DNA-based diagnostics in oncology 13 14th November 10:45-12:15 Dr M.Matějů Biochemical principles of anticancer treatment 14 16th November 10:45-12:15 Dr M.Matějů Tumour markers 15 21th November 10:45-12:15 Dr.
M.Vejražka Disorders of acid-base balance 16 23th November 10:45-12:15 Dr. J.
Pláteník Reactive oxygen and nitrogen species in the body, the antioxidant defence 17 28th November 10:45-12:15 Dr. J.
Pláteník Ageing 18 30th November 10:45-12:15 Dr. M.Vejražka Atherosclerosis 19 5th December 10:45-12:15 Prof.
J. Jonák Disorders of protein folding and their clinical consequences.
Prions 21 7th December 10:45-12:15 Dr. J.Krtil Non-enzymatic glycations, insulinoresistance, metabolic syndrome 22 19th December 10:45-12:15 Dr.
J. Pláteník Death of heart and neuronal cell: ischemia/reperfusion, excitotoxicity and neurodegeneration
Anotace
Základní molekulární principy vzniku a rozvoje chorobných stavů. Poruchy acidobazické a oxidoredukční rovnováhy (reaktivní formy kyslíku a dusíku), poruchy v uchování a expresi genetické informace, poruchy buněčné signalizace.