Syllabus
* Lectures
Elements and inorganic compounds important in biochemistry, toxicology and dentistry I.
Elements and inorganic compounds important in biochemistry, toxicology and dentistry II.
Elements and inorganic compounds important in biochemistry, toxicology and dentistry III.
Organic chemistry: stereochemistry, structures and classification of organic compounds
Hydrocarbons and their derivatives - biological and toxicological importance
Carboxylic acids and their derivatives
Chemical bond. Water, solutions, dissolution. Chemical activity. Dissociation. Ionic strength. Colloids. Diffusion. Osmolarity.
Acids and bases, pH. Neutralisation. Buffers.
Thermodynamics, thermochemistry. Chemical equilibrium and chemical kinetics. Catalysis.
Redox reactions. Basics of electrochemistry. Galvanic and electrochemical cell. Energetics of chemical reactions.
Heterocyclic compounds and derived substances. Alkaloids.
Lipids - structure and properties. Fatty acids.
Saccharides and polysaccharides: significance in biochemistry and dentistry.
* Seminars
Inorganic materials in dentistry: Amalgams. Toxicology of mercury.
Inorganic materials in dentistry: Metals and alloys.
Dental material science I: Polymer materials
Dental material science II: Composite materials
Dental material science III: Cements
Dental material science IV: Dental ceramic materials
Dental material science V: Gypsum products and investment materials.
Nomenclature of inorganic compounds.
Ionic equations. Coordination compounds.
Amino acids, proteins and enzymes
Calculations involving concentrations. Stoichiometric calculations.
Calculations involving pH, buffers.
Calculation of osmolarity and osmotic pressure.
* Practical lessons
Work with stomatologic plaster - dental cast
Analysis of amalgam and dental cement.
Demonstration of monomer in Duracryl resin. Reactivity of basic functional groups in organic compounds.
Protein precipitation. Dialysis. Gel filtration.
Galvanic cell in the mouth. Acid-base titration. Titration curves.
Buffers and buffer capacity. Estimation of pH and titratable acidity of selected beverages.
Annotation
The subject is focused on medical chemistry for dentist. Inorganic and organic chemistry concentrated on nutrition, toxicology and especially on stomatologic materials (alloys, amalgams, dental cements, silicates and synthetic materials).
The students should manage the basic work in the chemical laboratory, the inorganic, organic and biochemical analysis and acqaint with the principles of use of dental materials.