Sylabus
B81307 - CYTOLOGY AND GENERAL HISTOLOGY
Lectures
The Cell:
- Morphological and functional unit
- Structure and function of biologic membrane and cell membrane
- Membrane organelles (cell compartments) - structure and function
- The nucleus and its components
- Non - membrane cell organelles
- Cytoskeleton - structure, function
- Tissue specificity
- Cell inclusions - structure, function
- Specialisation of cell surface
- Exocytose, endocytose, trans-membrane transport
- The cell cycle, mitosis, meiosis
Tissues:
- Classification, basic structure and function
- Epithel - classification, structure, function
- Connective tissue - basic characterisation, extracellular matrix, its production, composition and functional significance o Cartilage - structure, function, classification o Bone - histogenesis, classification, structure, function o Dentin - structure, function
- Muscular tissue - o Characteristics of smooth and striated muscle o structure of muscle cells and fibres o ultrastructure of myofibrile o mechanisms of contraction
- Nerve tissue - o Neuron - structure, function; synapses - structure, function, regulatory function of neurotransmitters o Neuroglia - classification, structure, function o Nerve fibres and their envelopes (sheets)
- Blood - o composition and function of peripheral blood, blood corpuscles and plasma, o characteristics of blood corpuscles, structure, function o haematopoiesis - periods, stem and progenitor cells, regulation of haematopoiesis, detailed description of differentiation of blood corpuscles
Lymphatic system -
- lymphatic vessels, lymphatic organs
- principles of immunologic mechanisms, MMS
- lymphocytes, typology and function
Endocrine system -
- diencephalopituitary system, neurohumoral regulation
- endocrine glands, structure, function
- disseminated endocrine system
- autocrine, paracine, endocrine effect
Seminars and practical courses
Histological technique -
- Methods of cell and tissue studies
- Histological preparation (slice)
- Uptake, fixation, labelling, processing of samples
- Staining and dyes, basic and special methods used in histology
- Principles of histochemistry and immunohistochemistry
- Principles of electron microscopic techniques
- Section analysis
General histology -
- Epithelia - o characteristics, o classification, structure, function
- Connective tissue - cells and ECM o Visualisation of fibres o Visualisation of cells o Structure and function of different types of connective tissue
- Cartilage - structure, classification
- Bone - o Lamellar and fibrous bone o Intramembranous and endochondral ossification
- Blood - o Blood corpuscles o Production, staining and evaluation of blood smears o leukogramm (differential blood counting) o Bone marrow smears. morphology of developing blood elements
- Muscle tissue - skeletal muscle, myocardium, smooth muscle
- Nerve tissue - o methods in neurohistology o classification of neurons o CNS a PNS
Anotace
Processing of tissue samples for histological analysis; basic methods of histological dying; structure and function of human cell and its particular constituents; cell contacts and communication; microscopic and ultramicroscopic structure of tissues and their functional features; application of theoretical knowledge to analysis of preparations.