Oral cavity and its content. Structural specialization of oral mucosa. Histological structure of lip, tongue, gums, palate and tonsils. General structure and function of the oral salivary glands, saliva.
Teeth and their structure. Specialized tissues of teeth - enamel, dentin, dental pulp, and cementum.
Supporting tissues - periodontium (periodontal ligament), alveolar bone, gingival mucosa and junctional (attachment) epithelium.
Introduction into embryology. Development of germ layers. Neural crest and its derivatives.
Head formation, stomodeum, pharyngeal arches.
Formation of face, development of the oral and nasal cavities.
Derivatives of the pharyngeal arches, clefts, and pouches.
Development of the tongue and of endocrine glands derived from stomodeum and from the primitive pharynx.
Development of teeth. Early tooth development, epithelial-mesenchymal interactions during tooth development. Amelogenesis, dentinogenesis. Development of the root and periodontal ligament. Tooth eruption.
Development of the skull, neurocranium and viscerocranium.
Congenital defects of the orofacial region. Facial clefts and palatal clefts. Birth defects involving pharyngeal region.