Molecular aspects of cell signaling, its disorders and clinical implications

Syllabus

Charakterization of signaling molecules, signal receptors, signal pathways and molecular effector responses to signal transduction. Signaling of G-protein coupled signal receptors.

Signaling of tyrosine kinase receptors. Signaling of tyrosine kinase associated receptors.

Nitric oxide signaling. Cytokine signaling.

Nuclear receptor signaling. Adhesion receptor signaling.

Hypoxia induced signaling. Apoptotic signaling.

Signaling aspects of cholesterol biosynthesis regulation.

Annotation

The aim of this one-semester course is to provide the students the basic overview on mechanisms and functions of molecular signaling in cells, its disorders and clinical implications.