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IIC - 2. Pain

Class at Third Faculty of Medicine |
CMCP0233

Syllabus

Pathophysiology and psychophysiology of pain

Terminology used in pain physiology

Peripheral mechanisms of pain

Central mechanisms of pain

Central pain inhibitory mechanism, its neuroanatomical substrates and neurotransmitter systems

Classification of opioid receptors and their distribution in CNS

Measurement of pain

Psychological approaches to pain

Pain as a psychological phenomenon

Psychological factors influencing the rise and course of pain and reactions to it

Indication and application of psychological (counselling and psychotherapeutic) approaches in pain control

Aspects of pain in children

Pathophysiological and psychological aspects of pain in children

Pain measurement in children in regard of the age

Contact with the child with acute and chronic pain: as a source of information

Non-pharmacological approach to the pain in children

Pharmacology of pain

Opioid analgesics

Nonopioid analgesics

Determining of exemplary case studies

Schedule of pharmacotherapeutical design (problem, selection of drug group, concrete drug, drug form, doses, risks, individualization, economical aspects, further control)

Individual elaboration of appropriate case studies

Surgery of pain

Spinothalamic chordotomy - transsection of tractus spinothalamicus lateralis comissurotomy ? transsection of comissura anterior (mediolongitudinal myelotomy) central myelothermocoagulation ? thermal lesion at C1 or Th12 level thermocoagulation in dorsal root entry zone ? exclusion of the secondary pain pathway neuron in the dorsal roots of spinal cord electrostimulation methods stereotaxic methods in thalamic region intrathecal opiate application ? application of opiates into liquor spaces using permanent reservoirs

Anaesthesiological care and postsurgical pain

Anaesthesiological methods in pain therapy

Postoperative pain

Chronic and malignant pain

Obstetric analgesia

Therapy of pain in neurology

Acute and chronic pain

Headache

Primary headache: (migraine, tension type headache and related syndromes, cluster headache and related syndromes)

Secondary headache due to another cranial or extracranial disease.

Pains of Vertebral Column (vertebrogenic (spondylogenic) pain, radicular (neurogenic) pain

Pain control in cancer patients

Various types of pain in cancer patient ? somatic, visceral

Pain characteristics (acute and chronic pain)

The difference in pain control in cancer patient in comparison with non-cancer patient

Surgical therapy of pain (types of surgery)

Radiation therapy of pain (analgesic radiotherapy using external beam radiotherapy, ?half body irradiation?, brachytherapy using radioactive strontium in therapy of multiple bone involvement

Painkillers used in cancer patients

Psychotherapy as a part of complex care of cancer patient in pain

General rules for pain control in cancer patient

Psychiatric approach to pain

Psychiatric aspects of pain:

Psychogenic pain - somatoform pain disorder (ICD 10 category-F45.4)

Pain and pain treatment in the cognitive behavioural therapy

Psychopharmacology of pain

Case story clinical presentation

Annotation

?Pain? is a problem oriented-course, part of the module Theoretical Bases of Clinical Medicine. The curse includes pathological physiology, pharmacology and explains the mechanisms of pain of different origin and their treatment.