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Pharmacology

Class at Second Faculty of Medicine |
DA0107362

Syllabus

*The syllabus Pharmacology 2nd Medical Faculty

*Lectures and Seminars

Introduction to Pharmacology

Basic terminology, types of treatment, development of new drugs, medicines act

*General pharmacology

Pharmacokinetics

Absorption, distribution, elimination and biotransformation of drugs

Receptor theory, mechanism of drug actions

Mechanism of regulation, receptors, mediatros, agonists, antagonists

Interactions of drugs

Mutual effects of drugs, toxicity

Development of new drugs

Development of new drug, preclinical and clinical assessment, registration

*Special pharmacology

Pharmacology of the autonomic nervous system

Physiology, receptors, mediators, agonists, antagonists, mechanism of action

Parasympathetic nervous system - parasympathomimetics, parasympatolytics

Sympathetic nervous system - agonists, antagonists, sympathomimetics, sympatholytics

Cardiovascular system

Antiarhytmic drugs

Cardiac Arrhytmias, drugs affecting heart output, heartrate, classification

Therapy of heart failure

Heart failure, digitalis, positive inotropic effect, cardiac hypertrophy

Beta blockers

Beta receptors, classification, Clinic use and strategies

Drugs used in blood coagulation disorders

Diuretics

Mechanism of action, classification

Respiratory system

Drugs for Asthma treatment, mucolytics, cough preparations

Antihistmines

Histamin, pathofysiology, effects, H1 and H2 agonists, clinical use 1st and 2nd generation

Drugs used in GIT

Drugs and the liver, therapy of peptic ulcers, spasmolytic agents, motility stimulating agents, laxatives, therapy of diarhoe

Hypolipidemic drugs

Types of pareticles, types of disorders, statins, fibrates, nicotin acid

Drugs used in rheumatic disease and OA

NSAIDs, SYSADOA, DMOA

Analgetics - antipyretics

Effects, mechanism of action, dosage, main groups

Analgetics - opioids

Morfin and its derivates, analgetic receptors, mechanism of action, clinical use, combinations of analgetics

General anaesthetics

Neuromuscular blocking agents, classification, mode of action

Antibiotics

Classification and indications, mechanism of action

Penicillins, Cephalosporins, Macrolides, Tetracyclins, Aminoglycosides, Quinolones, Combination

Antiviral Drugs

Classificaton, specific use, AIDS, toxicity

Antidiabetic drugs

Classification, mechanism of action, oral antidiabetic drugs, insulins

Central nervous system Pharmacology

Mediators of CNS, classification, hypnotics and anxiolytics, drugs used in psychoses, antidepressant drugs, neuroprotective drugs

Korikosteroids

Pathophysiology, effects, indications, risks

Drug policy

Rationa, pharmacotherapy, drug reimbursement, drug utilization

*Seminars

General pharmacology

Prescrtiption of Drugs

Introduction to rational drug prescribing

Patient-drug concept

Prerequisites for earning credits in pharmacology, MA degree program

The Institute provides education/training of Czech and English-speaking students.

Education in Grade IV - pharmacology for Czech and English-speaking students.

Prerequisites for earning credits in pharmacology, MA degree program

Annotation

The study program will focus on general pharmacology, in particular on getting a thorough understanding of the mechanisms of action of pharmaceuticals and study of their fate within the body, development of side effects and drug-to-drug interactions and toxic effects of medicinal products within the body in general. Furthermore, the curriculum encompasses prescription of magistral formulas and drugs manufactured on a mass scale.

In special pharmacology, emphasis is placed, in addition to basic characteristics of individual drug classes, on treatment of individual nosological entities and rational use of drugs while adhering to generally applicable legal and professional regulations (e.g., guidelines for the management of particular diseases/conditions by the respective professional societies).