Syllabus
*The syllabus Pharmacology 2nd Medical Faculty
*Lectures and Seminars
Introduction to Pharmacology
Basic terminology, types of treatment, development of new drugs, medicines act
*General pharmacology
Pharmacokinetics
Absorption, distribution, elimination and biotransformation of drugs
Receptor theory, mechanism of drug actions
Mechanism of regulation, receptors, mediatros, agonists, antagonists
Interactions of drugs
Mutual effects of drugs, toxicity
Development of new drugs
Development of new drug, preclinical and clinical assessment, registration
*Special pharmacology
Pharmacology of the autonomic nervous system
Physiology, receptors, mediators, agonists, antagonists, mechanism of action
Parasympathetic nervous system - parasympathomimetics, parasympatolytics
Sympathetic nervous system - agonists, antagonists, sympathomimetics, sympatholytics
Cardiovascular system
Antiarhytmic drugs
Cardiac Arrhytmias, drugs affecting heart output, heartrate, classification
Therapy of heart failure
Heart failure, digitalis, positive inotropic effect, cardiac hypertrophy
Beta blockers
Beta receptors, classification, Clinic use and strategies
Drugs used in blood coagulation disorders
Diuretics
Mechanism of action, classification
Respiratory system
Drugs for Asthma treatment, mucolytics, cough preparations
Antihistmines
Histamin, pathofysiology, effects, H1 and H2 agonists, clinical use 1st and 2nd generation
Drugs used in GIT
Drugs and the liver, therapy of peptic ulcers, spasmolytic agents, motility stimulating agents, laxatives, therapy of diarhoe
Hypolipidemic drugs
Types of pareticles, types of disorders, statins, fibrates, nicotin acid
Drugs used in rheumatic disease and OA
NSAIDs, SYSADOA, DMOA
Analgetics - antipyretics
Effects, mechanism of action, dosage, main groups
Analgetics - opioids
Morfin and its derivates, analgetic receptors, mechanism of action, clinical use, combinations of analgetics
General anaesthetics
Neuromuscular blocking agents, classification, mode of action
Antibiotics
Classification and indications, mechanism of action
Penicillins, Cephalosporins, Macrolides, Tetracyclins, Aminoglycosides, Quinolones, Combination
Antiviral Drugs
Classificaton, specific use, AIDS, toxicity
Antidiabetic drugs
Classification, mechanism of action, oral antidiabetic drugs, insulins
Central nervous system Pharmacology
Mediators of CNS, classification, hypnotics and anxiolytics, drugs used in psychoses, antidepressant drugs, neuroprotective drugs
Korikosteroids
Pathophysiology, effects, indications, risks
Drug policy
Rationa, pharmacotherapy, drug reimbursement, drug utilization
*Seminars
General pharmacology
Prescrtiption of Drugs
Introduction to rational drug prescribing
Patient-drug concept
Prerequisites for earning credits in pharmacology, MA degree program
The Institute provides education/training of Czech and English-speaking students.
Education in Grade IV - pharmacology for Czech and English-speaking students.
Prerequisites for earning credits in pharmacology, MA degree program
Annotation
In the third year of the summer semester, teaching is in the form of lectures. Teaching is focused on acquiring essential knowledge in general pharmacology.
The basic mechanisms of drug action (pharmacodynamics) and the principles of movement and fate of drugs in the human body (pharmacokinetics) will be explained. The general principles of the action of substances in the organism are followed by lectures on the effect of substances on the autonomic nervous system.
In this phase, special pharmacology begins and clinically important topics have been selected, i.e. hypertension treatment, antiplatelet treatment, DM I and II treatment, the importance of glucocorticoids in treatment and antibiotics. As part of the explanation, the possible emergence of unwanted or toxic effects of substances and the emergence of drug interactions in the body will also be pointed out.
All the knowledge acquired in pharmacology I is necessary for follow-up teaching in the 4th year. (Pharmacology II).