Syllabus
INFECTIOUS DISEASES FOR 5th COURSE GENERAL MEDICINE
The syllabus:
Lesson I
Gastrointestinal diseases of infectious origin
Pathophysiology of gastrointestinal diseases (osmotic, inflammatory, secretory mechanisms of diarrhoea)
Incidence and epidemiology of infectious gastroenterites
Infectious gastroenteritis of viral and bacterial origin and foodborne toxigenic diarrhoea (clinical course, diagnosis, therapy, prophylaxis)
Differential diagnosis of infectious and non- infectious diarrhoea
Complications of infectious diarrheal diseases
Clinical picture, epidemiology, pathophysiology, complications, therapy, prophylaxis of Salmonellosis, Salmonella typhi and paratyphi, Cholera, E.coli gastroenteritis, Campylobacteriosis, Yersinia enterocolitica, Shigellosis, pseudomembranous enterocolitis, Rotavirus, Adenovirus, Norwalk virus gastroenterites and other viral gastroenterites, foodborne toxigenic diarrhea
Hemolytic-uremic syndrome
Aspects of prophylaxis of infectious diarrhea (vaccination)
Lesson II
Infectious inflammatory diseases of the liver
Pathophysiology of viral hepatites
Incidence and epidemiology of viral hepatites
Acute viral hepatitis A - pathophysiology, epidemiology, clinical course, diagnosis (laboratory and serologic markers), therapy, prophylaxis specific and non-specific
Acute viral hepatitis B - pathophysiology, epidemiology, clinical course, diagnosis (laboratory and serologic markers), therapy, prophylaxis specific and non-specific
Acute viral hepatitis C - pathophysiology, epidemiology, clinical course, diagnosis (laboratory and serologic markers) therapy, possibility of prophylaxis
Viral hepatitis D - pathophysiology, epidemiology, clinical course, diagnosis (laboratory and serologic markers), therapy, possibility of prophylaxis
Acute viral hepatitis E- pathophysiology, epidemiology, clinical course, diagnosis (laboratory and serologic markers) , therapy, prophylaxis
Viral hepatites G, F, TTV - new causes of viral hepatites?
Complications and sequelae of acute viral hepatites
Differential diagnosis of acute hepatites (infectious and non-infectious origin)
Chronic hepatitites B and C - incidence, clinical picture, laboratory and serologic markers, possibility of therapy and prophylaxis nowadays
Reye´s syndrome
Lesson III
Exanthematic diseases
Types of exanthems commonly, pathogenesis
Exanthematic diseases of bacterial and viral origin
Scarlet fever – epidemiology, pathogenesis, clinical course, diagnosis, therapy, and differential diagnosis
Toxic shock syndrome – history, epidemiology, pathogenesis, clinical course, diagnosis, therapy
Kawasaki syndrome – history, epidemiology, pathogenesis, clinical course, diagnosis, therapy
Rubella – epidemiology, pathogenesis, clinical course, diagnosis, differential diagnosis, complications, rubella in pregnancy, prophylaxis
Measles – epidemiology, pathogenesis, clinical course, diagnosis, complications, differential diagnosis, measles and immunity of organism, prophylaxis
Varicella (Chickenpox) – epidemiology, pathogenesis, clinical course, diagnosis, differential diagnosis, therapy, complications, varicella in pregnancy, varicella and immunodeficiency, prophylaxis
Herpes zoster – epidemiology, pathogenesis, clinical course, diagnosis, therapy
Megalerythema infectiosum – epidemiology, pathogenesis, clinical course, diagnosis, differential diagnosis, therapy, complications, megalerythema infectiosum in pregnancy
Exanthema subitum (Roseola infantum)– epidemiology, pathogenesis, clinical course, diagnosis, therapy, complications
Lesson IV
Lymphadenopathy
Occurrence of lymphadenopathy commonly, quick diagnosis is necessary
Viral causes of lymphadenopathy:
Adenovirus – epidemiology, clinical course, diagnosis, therapy
Infectious mononucleosis /virus Epstein-Barr, cytomegalovirus/ - epidemiology, pathogenesis, clinical course, diagnosis, therapy, complications
Parotitis epidemica (Mumps) – epidemiology, pathogenesis, clinical course, therapy, complications, therapy if complications, prophylaxis
Rubella, measles – clinical course exanthematic diseases
Gingivostomatitis herpetica (Aphthous stomatitis) – epidemiology, pathogenesis, clinical course, therapy, differential diagnosis
Bacterial cases of lymphadenopathy:
Infections of streptococci – angina, lymphadenopathy – epidemiology, pathogenesis, clinical course, diagnosis, therapy, complications
Infections of staphylococci – angina, lymphadenopathy, bacterial parotitis – epidemiology, pathogenesis, clinical course, diagnosis, therapy, complications
Tularaemia – history, epidemiology, pathogenesis, clinical course, types of tularaemia, diagnosis, therapy, complications
Diphtheria – epidemiology, pathogen
Annotation
Infectious diseases of GIT. Differential diagnosis of diarrhea.
Acute and chronic viral hepatitis, up-to-date therapeutic recommendation.Antibiotic treatment in clinical practice. Exanthematic infectious diseases.
Differential diagnosis of lymphadenopathy. Neuroinfections (bacterial meningitis, viral meningitis, differential diagnosis of meningeal features).
Sepsis, septic shock. AIDS, prevetion, therapy, diagnosis, opportunic infections.
Immunity disorders and infections. Respiratory tract infections.