Syllabus
In connection with sequencing of human genome and the other discoveries in biology there is an expansion of knowledge about molecular basis of human diseases, especially cancer. Molecular Pathology is the study of disease at the molecular level.
Translational Medicine is a rapidly growing discipline in biomedical research that aims to expedite the discovery of new diagnostic tools and treatments by using a multi-disciplinary, highly collaborative, "bench-to-bedside" approach. Molecular basis of cancer, epigenetic changes cooperating with genetic alterations to drive the cancer phenotype („Hallmarks of Cancer“) and some examples of translational research in human cancer will be mentioned during the course.
Annotation
The aim of the course is to acquaint postgraduate students with the latest knowledge about molecular basis of human diseases, especially cancer. Attention will be paid in particular to epigenetic processes and their impacts on neoplastic transformation and progression of tumours and selected nonneoplastic diseases.
Translation of new knowledge of disease processes, diagnostic or treatment techniques into routine clinical practice will be also mentioned.