Annotation
Human karyotype. Structural and numerical aberration of autosomes.
Sexual reproduction, meiosis, abnormalities of gonosomes. X-linked genes, X chromosome inactivation. Genetic manipulations - recombination of DNA, PCR, DNA sequencing.
DNA diagnostics. Production of recombinant molecules.
Gene therapy. Genetics of multicellular organisms, Mendel?s law, Morgan?s law. Clinical genetics - inborn errors of metabolism, prenatal diagnosis, genetic counselling.
Human genetics - pedigree analysis, siblings, genomics. Gene control of immunity, antibodies, monoclonal antibodies.
Immunologic tolerance, transplantation immunity. Population genetics - Hardy-Weinberg law - its application and consequences.
Evolution of species, evolution of Homo sapiens.