Syllabus
Lectures
Classical and new molecular targets for drugs, traditional and modern approaches to drug development. (Chladek 3)
Basic terms in pharmacoepidemiology and pharmacoeconomics. Comparative drug studies, trials of pharmacotherapeutic intervention, principles of evidence based medicine in pharmacology, pharmacotherapeutic guidelines, systematic reviews and meta-analyses. (Chladek 3)
Practical courses & seminars
Lecturers
Assoc. Prof. Jaroslav Chladek, M.Sc., Ph.D.
Assoc. Prof. Martin Štěrba, PharmD., Ph.D.
The role of "OMICS" technologies in pharmacological research: genomics, proteomics, transcriptomics and metabolomics (seminar).
New trends in pharmacokinetics (PK/PD) and pharmacodynamics, PK/PD of therapeutic proteins (seminar). PK/PD modelling (practical).
Population pharmacokinetics/pharmacodynamics and its value for personalized pharmacotherapy (seminar). Population PK/PD models for selected drugs (practical).
Annotation
The goal of the elective program is to introduce the methods used in selected areas of basic and clinical pharmacology including modern trends. The course includes practical training of the methods using computers and case studies from clinical practice.