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Pathobiochemistry and Disorders of Metabolism and Nutrition

Class at Faculty of Medicine in Hradec Králové |
FV086

Syllabus

Lecturers: prof. MUDr. Vladimír Blaha, CSc. prof. MUDr. Luboš Sobotka, CSc. prof. MUDr. Zdeněk Zadák, CSc. doc. MUDr. Alena Stoklasová, CSc.

MUDr. Eduard Havel, Ph.D.

MUDr. František Musil, Ph.D.    

Seminars and practical courses:

The applications of biochemical mechanisms in the clinical practice. Dyslipidaemias, their classification, phenotypes, pathophysiology. Management of dyslipidaemias - diet and drug treatment.

Case reports: dyslipidaemias – their treatment.

Malnutrition – metabolic changes. Anorexia mentalis, obesity – their treatment.

Diabetes mellitus - types, sources of energy. Case reports. Treatment and nutrition of a diabetic mellitus.

The assessment of energy sources available in PEN and EN, standard substrates, organ specific substrates.

The utilization of energy sources in critically ill patients. Indirect energometry, the introduction into the methods of metabolism monitoring.

Case reports: the strategy of volume supplement in patients with cardiovascular insufficiency.

Organ specific substrates in treatment of shock, sepsis, multiorgan insufficiency, liver and renal insufficiencies. Water and mineral supplementation.

Management of geriatric patients.

Consultation. Credit test.

Annotation

The metabolic disorders, their diagnostics and treatment are discussed. Substrates in parenteral and enteral nutrition – their choice and combinations.

Treatment of shock, sepsis, multiorgan insufficiency. The discussion is based on the application of knowledge of biochemistry and pathology that allows to improve the understanding of diseases and their adequate treatment.