Syllabus
Lectures:
General chemistry 1. Basic terms and categories 1.1 the subject and development of chemistry, its differentiation, interdisciplinary relations. Chemistry in the study of pharmacy 1.2 matter, field, motion and its forms, compounds, elements 1.3 basic empirical chemical laws, chemical notation, basic terms concerning elements and compounds 1.4 nomenclature of inorganic compounds 2. Atomic theory 2.1 development of atomic theory 2.2 contemporary atomic theory, subatomic particles, arrangement of electrons, protons, and neutrons, atomic models) 2.3 atomic nucleus (proton number, nucleon number, nuclides, natural and artificial radioactivity, physical, chemical, and biological effects of nuclear radiation, applications of radioactive nuclides to pharmacy and medicine) 2.4 arrangement of electrons (Bohr's atomic model, dualistic nature of electron, the quantum mechanical model of the atom) 3. Theory of chemical bonding 3.1 ionic relation (origin of ions, ionisation energy, electronic affinity, structure of ionic compounds) 3.2 the covalent bond (theory of valence bonds, theory of molecular orbitals, hybridisation of atomic orbitals, orientation of bonds in space, bond order, bond energy, polarity of covalent bonds, dipole moment, donor-acceptor bond) 3.3 metallic bond 3.4 weak (non-)bonding interactions (hydrogen bridge, van der Waals forces) 3.5 molecular structure and shape– valence bond (VB) theory (hybridization of orbitals), valence shell electron pair repulsion (VSEPR) theory 4 Dispersion systems 4.1 basic terms, classification, importance for pharmaceutical sciences and practice 4.2 solutions (preparation, properties of solutions, importance in biology and pharmacy) 4.3 ionisation in solutions 4.4 acids and bases (theories of acids and bases, relations between structure and acid-basic properties of compounds) 4.5 ionic product of water, pH 4.6 protolytic reactions 4.7 solubility product constant 5 Chemical reactions and their intercourse 5.1 reaction kinetics and thermodynamics 5.2 oxidation-reduction reactions 5.3 electrochemistry 6. Co-ordination compounds 6.1 basic terms 6.2 co-ordinate theory, Werner's approach, contemporary theory 6.3 types of co-ordination compounds, stereochemistry of co-ordination compounds 6.4 bioinorganic, pharmaceutical, medical, and selected technological aspects of chemistry of co-ordination compounds 6.5 nomenclature of co-ordination compounds 7. The periodic law and the periodic table of elements 7.1 classification of elements, importance of D. M. Mendeleev's periodic law 7.2 the periodic table of elements 7.3 the periodic law and the periodic table in relation to contemporary atomic theory
Inorganic chemistry 8. Chemistry of s- and p- elements and their compounds with regard to the biological and pharmaceutico-medical aspects 8.1 hydrogen, water 8.2 the noble gases 8.3 the alkali metals 8.4 the alkaline earth metals 8.5 the boron group 8.6 the carbon group 8.7 the nitrogen group 8.8 the chalcogens 8.9 the halogens 9 Chemistry of d- and f- transition elements and their compounds with regard to the biological and pharmaceutico-medical aspects 9.1 the scandium subgroup, lanthanides, actinides 9.2 the titanium subgroup 9.3 the vanadium subgroup 9.4 the chromium subgroup 9.5 the manganese subgroup 9.6 the iron triad 9.7 the palladium triad; the platinum triad 9.8 the copper subgroup 9.9 the zinc subgroup
Seminars: 1 Basic chemical terms, empirical formulas 2 Nomenclature and formulas of inorganic compounds 3 Structural (Lewis dot) formulas 4 Solutions - calculation of concentrations 5 Stoichiometric calculations 6 Acids and bases, acid-base reactions, calculations of pH, Ka, hydrolysis of salts 7 Oxidation number, oxidation and reduction - balancing of equations
Annotation
General Chemistry is fundamental to understanding other chemical disciplines. The subject deals with atomic structure, the theory of chemical bond, the periodic character of physical and chemical properties of elements and compounds and with the course of chemical reactions.
Inorganic chemistry gives a systematic survey of chemical elements and their compounds on the basis of the location of the elements in the periodic table; special emphasis is put on biological and pharmaceutical importance.