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Pharmaceutical Chemistry I

Class at Faculty of Pharmacy in Hradec Králové |
GAF341

Syllabus

Definition and characterization of the subject

Historical development of pharmaceutical chemistry

Sources of new drugs

Drug nomenclature

Structural factors affecting biological activity

Drug structure modifications

Physicochemical properties in relation to biological activity

Drugs affecting the central nervous system:

General anesthetics

Sedative-hypnotics

Anticonvulsants

Neuroleptics

Anxiolytics

Antidepressants

Psychostimulants

Hallucinogens

Antiparkinsonian agents

Opiate analgesics

Nonopiate analgesics

Nonsteroidal anti-inflammatory agents

Antiemetics

Antitussives

Expectorants

Drugs affecting the peripheral nervous system

Local anesthetics

Skeletal muscle relaxants

Annotation

Pharmaceutical Chemistry is a specific pharmaceutical subject representing the link between chemical and biological disciplines. Its task is to provide students with a complex understanding of drug and auxiliary substance chemistry.

The drugs are studied from the point of view of their rational selection and preparation, quality criteria, suitable ways of storage, structure-activity and structure-metabolism relationships, and practical usage. The brief information concerning mechanisms of drug action covered in this subject forms the basis for a more profound study of this topic in pharmacology.

This subject belongs to the state final examination group of subjects.