Syllabus
General lectures
Clinical pharmacy and risk management in pharmacotherapy incl algorithms, contraindication, DDI, medication errors, signal indicator of risk
Risk minimization (ADR, DDI,CI medication errors), maximization of effect, cost effectiveness , polypharmacotherapy
The meaning of laboratory examinations to evaluate therapeutic and adverse effect of medicines
Explicit and implicit tools for evaluation of pharmacotherapy in elderly and their use in clinical practice
Clinical pharmacokinetics as a tool for individualization of pharmacotherapy
Medication review - methods and how to use it in pharmaceutical care
Drug induced toxicity, syndrome of withdrawal, loss of effectiveness in clinical practice
Management of clinical pharmacy on ward - challenges in barriers
Specialized lectures: The aspects of rational approach of individualization of pharmacotherapy in selected groups of patients and pharmacotherapy
Infection disease and prophylaxis
Anxiolytic, sedative agents; antidepressive agents in elderly
Schizophrenia, bipolar disease, depression
Antiepileptic, antiparkinson and cognitive agents
Clinical pharmacy management in neonatology and pediatric disease
Clinical pharmacy management by elderly, cause and management of polypharmacotherapy
Kidney failure (causes, consequences, changes of pharmacokinetics, rational pharmacotherapy)
Liver failure (causes, consequences, changes of pharmacokinetics, rational pharmacotherapy
Drugs for cardiovascular disease
Thrombophilia and bleeding stages, prophylaxis of thrombus building
Clinical pharmacy in oncology introduction and solid cancers
Clinical pharmacy in hemato-oncology
Rational pharmacotherapy of changes of inner environment
Palliative treatment
Annotation
The aim of subject is to focus more deeply on knowledge and skills in rational use of medicines in nosologic units not discussed in Clinical Pharmacy 1 and basic knowledge regarding basic concept and principles of risk minimization management of pharmacotherapy. Subject is preparing for subject Clinical pharmacy care and for state exam for student with internal specialization for clinical pharmacy.
Subject contents lectures and interactive lectures focusing on 1/ knowledge about disease management non discussed in Clinical pharmacy 1 (ethiopatogenesy, risk factors of disease, complication and risk factors of complication; relevant diagnostic method for rational choice of medicines and of a control of their effect and effectiveness, definition of relevant aims of treatment and basic strategies of acute and chronic form of disease respectively). 2/basic principles of risk minimization of pharmacotherapy (adverse drug reaction, drug-drug interactions, contraindications, medication errors). We will focus on different algorithms – mainly algorithm SAFE (signals or indicators of population and individual risk of pharmacotherapy, the analyzes of clinical significance; methods of prevention and treatment of risk). 3/ medication review in all disease lectured in Clinical pharmacy 1 and 2.