Syllabus
Pharmacology of central nervous system (part II)
Overview of neurotransmitters
Anxiolytic and hypnotic drugs
Antipsychotic drugs
Antidepressant drugs
Antiepileptic drugs.
Overview of centrally acting muscle relaxants
Opioid analgesics
CNS stimulants. Psychotomimetic agents (hallucinogens)
Ethanol – pharmacology, toxicology
Pharmacology of inflammation and immune response
Histamine. Histamine H1 receptor antagonists
Non-steroidal anti-inflammatory drugs.
Pharmacotherapy of rheumatoid arthritis; pharmacotherapy of gout arthritis
Immunomodulators: Immunosuppressant drugs. Overview of immunostimulants
Pharmacology of the endocrine system
Thyroid hormones. Treatment of hypo- and hyperthyroidism
Diabetes mellitus. Treatment with insulin, oral hypoglycaemic agents and other antidiabetic drugs.
Hormones of adrenal cortex: Glucocorticoids
Bone metabolism: Pharmacotherapy of osteoporosis
Pharmacology of the blood and haematopoietic system
Drugs affecting haemostasis and fibrinolysis
Drugs affecting the haematopoietic system: Treatment of anaemia by iron, folic acid, vitamin B12 and erythropoietin. Overview of other haematopoietic growth factors
Pharmacology of the respiratory system
Pharmacotherapy of bronchial asthma
Chronic obstructive pulmonary disease.
Drugs used for cough
Pharmacology of the gastrointestinal tract
Treatment of peptic ulcer disease
Drugs affecting vomiting
Therapy of constipation and acute diarrhoea: laxatives and antidiarrheal agents
Pharmacology of the reproductive system
Female sex hormones, therapeutic use: Hormonal contraception. Hormone replacement therapy
Male sex hormones. Anabolic steroids. Overview of treatment of erectile dysfunction and benign prostatic hyperplasia.
Drugs acting on the uterus
Chemotherapy of infections
Antibacterial drugs
Sulfonamides. Trimethoprim
β-lactam antibiotics - penicillins
β-lactam antibiotics – cephalosporins and other β-lactam antibiotics. Bacitracin. Vancomycin.
Tetracyclines. Aminoglycosides
Macrolides. Lincosamides. Chloramphenicol.
Fluoroquinolones.
Metronidazole. Nitrofurantoin. Locally used antibiotics.
Antimycobacterial agents
Antituberculosis drugs. Short overview of antileprosy drugs
Antiviral agents
Antifungal drugs
Therapy of protozoal infections: malaria, trichomoniasis, toxoplasmosis, amoebosis. Short overview of other protozoal infections and their treatment modalities.
Anthelminthic drugs
Cancer chemotherapy
Overview of anticancer drugs including targeted therapy – modes of action, side effects
Annotation
Pharmacology is a scientific discipline studying the interactions of drugs with the organism both in the sense of pharmacokinetics (the fate of the drug in the organism) and pharmacodynamics (effect of drugs on the organism). These interactions are studied at all levels (molecular, cellular, organ, whole organisms).
Pharmacology teaching in the “Pharmacy study program” is divided into two immediately adjacent parts: Pharmacology I (taught in winter semester of the 3rd year) and Pharmacology II (taught in summer semester of the 3rd year). Students will first learn about the general rules of pharmacokinetics (absorption, distribution, metabolism and excretion) and pharmacodynamics (mechanisms of drug effects, adverse reactions, principles of drug-drug interactions). Subsequently, topics of special pharmacology are discussed according to individual organ systems (e.g. cardiovascular, CNS, endocrine...). In the course of pharmacology, emphasis is also placed on the clinical aspects of drug effects in humans. The knowledge gained subsequently enables the pharmacist, in collaboration with a physician, to contribute to rational, safe and effective pharmacotherapy.
Pharmacology II is taught in the summer semester of the 3rd year immediately following the subject Pharmacology I (winter semester of the 3rd year). The subject of Pharmacology II focuses on the following thematic areas:
Special pharmacology
Pharmacology of the central nervous system (part II)
Pharmacology of inflammation and immune response
Pharmacology of the endocrine system
Pharmacology of the blood and haematopoietic system
Pharmacology of the respiratory system
Pharmacology of the gastrointestinal tract
Pharmacology of the reproductive system
Chemotherapy of infections
Cancer chemotherapy