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Toxicology for pharmaceutical sciences

Class at Faculty of Pharmacy in Hradec Králové |
GAPS158

Syllabus

GENERAL TOXICOLOGY  

Introduction, history and scope of toxicology General principles of toxicology Toxicokinetics Approach to the poisoned patient  

Toxicity test methods (in vivo, in vitro)  

  APPLIED TOXICOLOGY  

Target organ toxicity and biomarkers  

Toxicology of air borne agents  

Toxicology of blood borne agents  

Cardiotoxic agents  

Nephrotoxic substances  

Toxicology of essential metals  

Toxicology of heavy metals

GENERAL TOXICOLOGY

Introduction, history and scope of toxicology General principles of toxicology Toxicokinetics Approach to the poisoned patient

Toxicity test methods (in vivo, in vitro)

  APPLIED TOXICOLOGY

Target organ toxicity and biomarkers

Toxicology of air borne agents

Toxicology of blood borne agents

Cardiotoxic agents

Nephrotoxic substances

Toxicology of essential metals

Toxicology of heavy metals    

Annotation

Toxicology for pharmaceutical sciences addresses toxic effects of exogenous substances, especially medicines, on the living organism. First, the general principles will be explained (basic concepts, toxicokinetics, general principles of poisoning therapy, the most important antidotes, etc.).

The special toxicology will focus on drug-induced organ toxicity (cardiovascular, respiratory, hepatotoxicity, etc.), and also on the toxicity of the most common addictive substances including ethanol.