Syllabus
Definition and characterization of the subject
Historical development of pharmaceutical chemistry
Sources of new drugs
Drug nomenclature
Structural factors affecting biological activity
Drug structure modifications
Physicochemical properties in relation to biological activity
Drugs affecting the central nervous system:
General anesthetics
Sedative-hypnotics
Anticonvulsants
Neuroleptics
Anxiolytics
Antidepressants
Psychostimulants
Hallucinogens
Antiparkinsonian agents
Opiate analgesics
Nonopiate analgesics
Nonsteroidal anti-inflammatory agents
Antiemetics
Antitussives
Expectorants
Drugs affecting the peripheral nervous system
Local anesthetics
Skeletal muscle relaxants
Annotation
Pharmaceutical Chemistry is a specific pharmaceutical subject representing the link between chemical and biological disciplines. Its task is to provide students with a complex understanding of drug and auxiliary substance chemistry.
The drugs are studied from the point of view of their rational selection and preparation, quality criteria, suitable ways of storage, structure-activity and structure-metabolism relationships, and practical usage. The brief information concerning mechanisms of drug action covered in this subject forms the basis for a more profound study of this topic in pharmacology.
This subject belongs to the state final examination group of subjects.