Syllabus
Pharmaceutical-chemical aspects of central and vegetative nervous system drugs.Pharmaceutical-chemical aspects of the blood and blood system influencing drugs.Pharmaceutical and chemical aspects of the digestive and excretory system affecting drugs.Pharmaceutical and chemical aspects of bacterial and viral infections chemotherapeutics.Pharmaceutical-chemical aspects of cancer chemotherapeutics.Pharmaceutical-chemical aspects of vitamins and hormones.Other requirements are individually focused on the specific practical orientation of the dissertation theses.
Annotation
Pharmaceutical chemistry includes the theoretical and the systematic part. In the theoretical part, besides the historical aspects of drug development, sources of their acquisition, attention is also paid to nomenclature issues.
Wider attention is paid to the importance and influence of the chemical structure, including their modifications, on the pharmacokinetic and pharmacodynamic processes that take place when the drug is administered to the organism. The causal link between the chemical structure and drug stability as well as assumptions about possible interactions (chemical incompatibilities) are also discussed.
The systematic part classifies drugs according to the nature and type of their use (indication), i.e. in terms of their function. The chemical scaling remains in second place.
It is thus possible to compare drugs that are close to their clinical use, although they are different in mechanism of action or chemically. The chosen method of classification not only illustrates the logical link between pharmaceutical chemistry and pharmacology, but is also significant in terms of practice.
It corresponds to today's commonly used drug distribution within their Anatomical Therapeutic Chemical classification (ATC). A specific area of pharmaceutical chemistry is to study the relationships between the chemical structure and the biological properties of chemically defined substances and to use this knowledge to design and develop new, more efficient and safer substances.
Mastering pharmaceutical chemistry, along with other knowledge, enables in many cases to predict not only the prediction of biological activity but also other properties necessary for the handling, preservation and practical use of pharmaceuticals.