Syllabus
Definition and characterization of the subject
Historical development of pharmaceutical chemistry
Sources of new drugs
Drug nomenclature
Structural factors affecting biological activity
Drug structure modifications
Physicochemical properties in relation to biological activity
Drugs affecting the central nervous system
Drugs affecting the peripheral nervous system
Drugs affecting the autonomic nervous system
Histamine and antihistamines
Drugs affecting blood and the cardiovascular system
Drugs affecting the gastrointestinal tract and kidney
Vitamines
Hormones
Antiinfective and antiinvasive agents
Annotation
Medicinal chemistry provides a comprehensive picture of drugs and chemical substances. Medicinal chemistry is the interdisciplinary science, chemical (inorganic and organic chemistry, physical chemistry and biological disciplines (chemistry, pharmacology, molecular biology, microbiology, toxicology).
Understanding of structure-activity relationships (SAR) gives to all graduates of this type study specific ability in all fields of drug research. Medicinal chemistry can be seen as a subject with a connecting function between chemical, biological and pharmaceutical sub-disciplines specifically.
Connecting of pharmaceutical chemistry with other knowledge allow the prediction of biological activity, but also other characteristics necessary for the handling, storage, and practical implementation of provides a comprehensive set of knowledge, of which allows some cooperation with other specialists in pharma industry.