Syllabus
State exam in clinical pharmacy is divided into 3 areas – section A, B,C
Section A – nosologic units
Student is able to define: a/ aim of treatment; b/ main possibility of diagnostic procedures what is necessary for rational choise of medicines; c/ strategy of acute and chronic phase of disease (to add evidence, if they exist and duration of intervention; d/ to disciss different possibilities of errors by reaching of aim (selection of dosing interval, way of administration of medicine, medication non-adherence, lifestyle, co-medication incl. OTC, monitoring of effects of medicines.
Arterial hypertension
Congestive heart failure
Tachyarrhythmias
Painful form of ischemic heart
Peripheral artery disease
Deep venous thrombosis
Stroke
Chronic pain
Acute pain
Primary and secondary prevention of atherosclerosis
Peptic ulcer
Gastroesophageal reflux disease
Diarrhea
Constipation
Chronic bowel inflammation
Pancreatitis
Renal failure
Asthma bronchial
Chronic obstructive pulmonary disease
Depression and phobia
Dementia
Schizophrenia
Bipolar disease
Epilepsy
Parkinson disease
Headache
Benign prostate hypertrophy and low urinary tract syndrome
General principles of rational use of antibiotics
Infection of respiratory tract
Infection of urogenital tract
Systemic viral disease
Anemia
Hypo/hyper-thyreosis
Gout
Rheumatoid arthritis
Sleep disturbances
Diabetes mellitus
Osteoporosis
Osteoarthritis
Leukemia
Section B:
Analysis of adverse effect and signals of ADR and their management by algorithm of three pillars: 1/ theoretical risk factors; 2/ possibilities of monitoring of ADR and relevant risk factors and 3/ relevant management of risk minimization on the level of a/ administration of medicines; b/ medication adherence; c/ monitoring; d/medication review; e/ lifestyle; f/ complementary treatment with OTC medication and food supplements.
Hypo/hyperkalemia
Hypomagnesemia
Hypercalcemia, hypocalcemia
Hypoglycemia, hyperglycemia
Acidosis, alkalosis
Bradycardia, tachycardia
Visas failure
Constipation
Diarrhea
Cough
Concentration of creatinine
Hyperuricemia
Creatinkinasis high activity
ALT, AST high activity
Hyperlaktemia and lactic acidosis
QT interval prolongation
Elderly – basic risks of pharmacotherapy and how to minimize them
Pregnant and bearing women - basic risks of pharmacotherapy and how to minimize them
Children - basic risks of pharmacotherapy and how to minimize them
Patients by kidney failure - basic risks of pharmacotherapy and how to minimize them
Patients with liver failure- basic risks of pharmacotherapy and how to minimize them
Genomic signals of risk and use genomic principles in individualization of pharmacotherapy
Signals of non appropriate use of antibiotics
Pharmacokinetic signals of risk of pharmacotherapy and use pharmacokinetic principles in individualization of pharmacotherapy
Pharmakoepidemiologic signals of risk of pharmacotherapy and their use by creating of signals and minimize a risk of pharmacotherapy by algorithm SAFE
Section C: student prepares in the word during study 20 cases and will analyze them regarding analysis of goals and risk of pharmacotherapy using algorithm SAFE
He will present one of this study selected during exam
The Doctoral State Exam from the Social Pharmacy
Exam topics will be discussed from the point of view of general principles of management, regulation and use of tools to achieve the objectives of different policies (health, medicines, antibiotics, social), regulatory instruments to ensure availability, quality, efficacy and safety of pharmaceuticals and an analysis of the effectiveness of regulatory measures from an international perspective critical analysis of experience in the Czech Republic and inclusion in the international and historical context. There will be selected three topics to student.
Characteristics developmental stage of pharmacy and their reflection in the Czech national history, position and role of pharmacy in the development of health services
Ph
Annotation
Doktorská státní zkouška z klinické farmacie je rozdělena do 3 oblastí- Sekce A, B, C:
Sekce A:
U nosologických jednotek je student doktorského studia schopen definovat cíle léčby, základní možnosti diagnostiky nutné pro racionální volbu léčiv, strategie léčby u akutní a chronické fáze nemoci (doložit důkazy – jsou-li- že je dosaženo cílů léčby, rychlost, délka intervence, rozdíly) a uvést různé možnosti pochybení při dosahování cílů léčby (volba dávkování, časování, způsob podání léčiva, lékové non-adherence nemocného, režimová opatření, komedikace včetně OTC, monitorování léčby, atd.).
Strategie související s farmakoterapií definovat základní dávkové schémata a základní rizika - NÚ, lékové interakce, kontraindikace a obvyklá léková pochybení a hledat způsob jejich minimalizace pomocí nástrojů farmaceutické péče: způsob podání, míra lékové adherence, monitorování, režimová opatření, revize farmakoterapie a doplňková léčba bez předpisu).
Sekce B:
Analýza nežádoucích účinků ev. signálů NÚ a jejich řešení pomocí tří pilířů: 1/ teoretické rizikové faktory; 2/ možnosti monitorování NÚ a relevantních rizikových faktorů a 3/ relevantní způsoby minimalizace rizika na úrovni způsobu podání, lékové adherence, monitorování, revize farmakoterapie, režimových opatření, podpůrné léčba OTC léčivy a potravními doplňky. sekce C: student nasbírá do termínu SZZK 20 kazuistik a zpracuje je – analyzuje dosažení cílů a minimalizuje rizika formou algoritmu SAZE
Komise vybere jednu kazuistiku a ta bude v rámci zkoušky diskutována
Social pharmacy state exam
Exam topics will be discussed from the point of view of general principles of management, regulation and use of tools to achieve the objectives of different policies (health, medicines, antibiotics, social), regulatory instruments to ensure availability, quality, efficacy and safety of pharmaceuticals and an analysis of the effectiveness of regulatory measures from an international perspective critical analysis of experience in the Czech Republic and inclusion in the international and historical context. There will be selected three topics to student.