Syllabus
Introduction and definition of the topic definition of food supplements and food supplements, differences between the drug and the food supplement, use of food supplements as preventive means, validity of chemical substances (total mixtures of substances) that are not based on chemical drugs, requirements for the so-called biological effect, the difference between nomenclature categories, legislation in the EU, related regulations in the Czech Republic, current state, hygienic standards of some substances whose important nutraceuticals.
Antioxidants pathophysiology of oxidative stress (RNOS), the importance of oxidizing substrates in the body, their positive and negative effects on human tissues, the basis for the development of diseases of civilization, the possibility of interfering with the metabolism of RNOS at various levels, systematics of used substances.
Adaptogens definition of general adaptation syndrome, analysis of pathophysiological consequences of stress, possibilities of intervention at selected levels, systematics of used means.
Substances for calming or stimulating the central nervous system analysis of the pathophysiological condition, enumeration of levels at which the intervention can be performed, substances and plants use, their doses and interactions with pharmacotherapy. substances used in neurodegenerative diseases (Alzheimer's and Parkinson's disease; pathophysiology of processes, possibilities of adjuvant use of substances, substances used, their doses and interactions with pharmacotherapy)
Substances used in chronic fatigue syndrome (CFS) pathophysiology of CFS, systematics of used compounds and natural mixtures. substances used, their doses and interactions with pharmacotherapy.
Immunostimulants definition of non-specific and specific immunity, possibilities of intervention, pathophysiology of immunodeficits, possibilities of use of nutraceuticals, substances and plants use, their doses and interactions with pharmacotherapy.
Substances affecting the risk of neoplasms (chemopreventives) and used in the treatment of cancer pathophysiology of carcinogenesis, influencing by external conditions (exposure to harmful factors of the external environment, diet, etc.), the possibility of intervention with nutraceuticals in the prevention of neoplasms and slowing the progression, the possibility of adjuvant action of nutraceuticals in chemotherapy, radiotherapy, increasing their effectiveness or reducing adverse effects on other tissues, substances and plants use, their doses and interactions with pharmacotherapy.
Substances for influencing the metabolism of diabetes and affecting body weight analysis of factors influencing the development of type 2 diabetes mellitus, overweight and obesity, the possibility of interfering with unwanted development by the action of nutraceuticals, substances and plants use, their doses and interactions with pharmacotherapy.
Substances used in functional damage to the cardiovascular system pathophysiology of cardiovascular diseases, analysis of disease states in which the use of nutraceuticals as preventive or adjuvant agents or as part of therapy is possible. substances and plants use, their doses and interactions with pharmacotherapy.
Substances used for tissue protection hepatoprotectives, substances used in the protection of germinal and ocular tissues the possibility of intervention in undesirable processes by the action of nutraceuticals, substances and plants use, their doses and interactions with pharmacotherapy.
Substances to increase the hygiene of the digestive and urogenital system brief analysis of digestive processes, metabolism and disharmony, substances and plants use, their doses and interactions with pharmacotherapy.
Substances used during menopause and andropause analysis of hormonal conditions during menopause and andropause (pre- and post-climacteric conditions, benign prostatic hyperplasia, loss of libido), substances and plants use, their doses and interactions with pharmacotherapy.
Annotation
The subject provides targeted information about the physiological and pathophysiological processes, which assert during the human nutrition and which can influence the development of health of individual person. With this commentary is connected the systematic part, which mentions the application of food supplements or food of new type, their legislative position in EU countries and legislative specifics in Czech Republic.
They are browsed the individual substances and group of substances (natural, biotechnological and synthetic origin), which do not have the character of drug, and which are presently commonly used in the EU territory and especially as a precautionary preparations, which could protect against the development of civilization diseases and their pathogenesis (oxidative stress, general adaptation syndrome, cancerogenesis), or are used in the certain live periods, but also like the tool, which is possible to use as a adjuvant with the effective pharmacotherapy, without bringing the negative interactions. There is also the information about the preparations which are attractive, which are not authorized in CR (EU), however, in other countries are commonly used (especially USA, China, Japan).
As a part of the subject there is the caution on the substances, which commonly occur in food and can affect health or pharmacotherapy, their safe dosages, important interaction or side effects.