State exam in clinical pharmacy is divided into 3 areas – section A, B,C
Section A – nosologic units
Student is able to define: a/ aim of treatment; b/ main possibility of diagnostic procedures what is necessary for rational choise of medicines; c/ strategy of acute and chronic phase of disease (to add evidence, if they exist and duration of intervention; d/ to disciss different possibilities of errors by reaching of aim (selection of dosing interval, way of administration of medicine, medication non-adherence, lifestyle, co-medication incl. OTC, monitoring of effects of medicines.
Arterial hypertension
Congestive heart failure
Tachyarrhythmias
Painful form of ischemic heart
Peripheral artery disease
Deep venous thrombosis
Stroke
Chronic pain
Acute pain
Primary and secondary prevention of atherosclerosis
Peptic ulcer
Gastroesophageal reflux disease
Diarrhea
Constipation
Chronic bowel inflammation
Pancreatitis
Renal failure
Asthma bronchial
Chronic obstructive pulmonary disease
Depression and phobia
Dementia
Schizophrenia
Bipolar disease
Epilepsy
Parkinson disease
Headache
Benign prostate hypertrophy and low urinary tract syndrome
General principles of rational use of antibiotics
Infection of respiratory tract
Infection of urogenital tract
Systemic viral disease
Anemia
Hypo/hyper-thyreosis
Gout
Rheumatoid arthritis
Sleep disturbances
Diabetes mellitus
Osteoporosis
Osteoarthritis
Leukemia
Section B:
Analysis of adverse effect and signals of ADR and their management by algorithm of three pillars: 1/ theoretical risk factors; 2/ possibilities of monitoring of ADR and relevant risk factors and 3/ relevant management of risk minimization on the level of a/ administration of medicines; b/ medication adherence; c/ monitoring; d/medication review; e/ lifestyle; f/ complementary treatment with OTC medication and food supplements.
Hypo/hyperkalemia
Hypomagnesemia
Hypercalcemia, hypocalcemia
Hypoglycemia, hyperglycemia
Acidosis, alkalosis
Bradycardia, tachycardia
Visas failure
Constipation
Diarrhea
Cough
Concentration of creatinine
Hyperuricemia
Creatinkinasis high activity
ALT, AST high activity
Hyperlaktemia and lactic acidosis
QT interval prolongation
Elderly – basic risks of pharmacotherapy and how to minimize them
Pregnant and bearing women - basic risks of pharmacotherapy and how to minimize them
Children - basic risks of pharmacotherapy and how to minimize them
Patients by kidney failure - basic risks of pharmacotherapy and how to minimize them
Patients with liver failure- basic risks of pharmacotherapy and how to minimize them
Genomic signals of risk and use genomic principles in individualization of pharmacotherapy
Signals of non appropriate use of antibiotics
Pharmacokinetic signals of risk of pharmacotherapy and use pharmacokinetic principles in individualization of pharmacotherapy
Pharmakoepidemiologic signals of risk of pharmacotherapy and their use by creating of signals and minimize a risk of pharmacotherapy by algorithm SAFE
Section C: student prepares in the word during study 20 cases and will analyze them regarding analysis of goals and risk of pharmacotherapy using algorithm SAFE
He will present one of this study selected during exam
State exam of clinical of social pharmacy according to specialization of student