Syllabus
Preliminary schedule: Block 1: molecular aspects and developmental roles of TEs · Week
1. Lecture: Introduction [CLP]. · Week
2. Lecture: TE families, modes of actions and evolution [CLP]. · Week
3. Lecture: Epigenetic silencing of TEs by host genomes [LF]. · Week
4. Lecture: TEs and sexual reproduction [CLP]. · Week
5. Homework. · Week
6. Knowledge consolidation. Presentations. Essay practice [CLP]. Block 2: evolutionary implications of TEs · Week
7. Lecture: Natural selection and TEs [CLP]. · Week
8. Lecture: Stress impact on TE activity [CLP]. · Week
9. Lecture: Molecular domestication of TEs [RB]. · Week
10. Lecture: TEs and biodiversity [CLP]. · Week
11. Knowledge consolidation. Presentations. Essay practice [CLP]. Block 3: hands on TEs! (practical classes) One week in January. Teachers: VC and CLP. Detailed program TBA. · Day
1. Profiling the epigenetics of TEs
1. · Day
2. Profiling the epigenetics of TEs
2. · Day
3. Profiling the epigenetics of TEs
3. · Day
4. Identify and annotate TEs in genomes with RepeatExplorer
1. · Day
5. Identify and annotate TEs in genomes with RepeatExplorer
2.
Annotation
This course will be held in English.
Transposable elements (TEs), since their discovery, have been considered either as useless pieces of DNA, as selfish parasitic genes or as major elements driving biodiversity. The aim of this course is to bring a holistic knowledge of TEs, from the molecular mechanisms underlying their function to their impact on populations and species in eukaryotes. It will involve lectures gathering current research issues as well as practicals involving modern tools used in current research.