Annotation
The aim of the lecture is to explain fundamentals of molecular biology in the historical context of the development of molecular genetics. In addition to the necessary facts, emphasis is given on explaining experiments that led to fundamental discoveries of molecular biology.
All molecular processes are explained in representatives of all three major forms of life - bacteria, archaea and eukaryotes in parallel. If there are differences in the level of replication and manifestation of genetic information between unicellular and multicellular organisms, they are also discussed.
Impact of the discussed facts on the possible treatment of microbial and parasitic infections is explained. The lecture refers to the practical aspects including medical practice whenever it is possible.
Historical milestones of molecular biology, genomics and proteomics, and the basics of genetic engineering are also discussed.