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Molecular and Immunologic mechanism of viral pathogenesis

Class at Faculty of Science |
MB140P91

Syllabus

Mechanisms of viral restriction and adaptation during acute, persistent, chronic and latent infection

1. Types of infection (acute, persistent, chronic, slow), restriction / innate and natural immunity; interferon(s) - cytokines

2. Acute infections: influenza virus, restriction and adaptation

3. HIV persistence and latency

4. Persistent and latent phase of infection by other retroviruses

5. Million years taking persistence of retroviruses: endogenous retroviruses

6. Persistent and latent infection: active and passive role of the virus (herpesviruses and retroviruses)

7. Chronic type of infection, LCMV and HBV

8. Virus restriction during and after virus entry into the cell - restriction factors

9. Zoonoses, viral receptors and adaptation

10. Vaccines (KT) + students presentations

11.  Control of virus infection in the host population

12. Students‘ round table discussion (viral tropism)

Annotation

Medical Virology and Viral Pathogenesis is an advanced level virology course that focuses on various aspects of viral infection, virus spread, host response to viral infections, latency and persistency. This course is oriented primarily to the needs of biology and biomedical students at the upper undergraduate and advanced academic degrees (Master and Ph.D. candidates) who wish to expand their knowledge in human virology beyond the basic microbiology level (which is required).

Students will have the opportunity to learn the most recent state of knowledge on various aspects of human virology. Proposed course places particular emphasis on viruses which cause disease in humans.

During the period of anti-epidemic measures, the lectures will be given online via the Google-Meet communication platform at the time indicated in the schedule.