Syllabus
Historical review, Oogenesis and folliculogenesis, Spermatogenesis, Spermiogenesis, Transcription and translation in germinal cells, Oocyte maturation and fertilization, Molecular biology methodologies, Embryo development, Overview of different types of development, mouse embryonic development, gene expression in early embryonic development chromatin structure, Embryonic stem cells, Induced pluripotency, RNA interference, Vertebrate cloning, Transgenic and GMO animals, Visit of laboratories of Institute of Animal Physiology and Genetics AS CR Libechov
Annotation
Please note, the lectures are given in czech language only.
The lectures will be focussed to the recent knowledge about generation of male and female germ cells and to the regulation of these processes. Attention will be paid also to the events associated with fertilization and embryo development on mammals. The impact of present results to new biotechnologies including embryo cloning will be discussed.