Syllabus
We will cover the immune system from these perspectives: 1/ Principles and models of IS - Immune system basics: conflict of concepts - Immune response: class, polarization and organization - Innate immunity: the danger model & the triggers 2/ Innate IS - Pattern recognition receptors anywhere: adjuvants & inflammation - Antigen processing and presentation: MHC molecules I / II & APCs - Antigen processing and presentation: non-classical MHC and crosspresentation 3/ Adaptive IS and NK cell/T cell dichotomy - Introduction to adaptive immunity: Antigen & Immunoreceptors - Molecular mechanisms of TCR / BCR diversity - NK cells & NK receptors: missing-self & alloreactivity 4/ Immune system in health and disease - Cytokines, chemokines, migration & signaling - Clinical immunology: Immunopathologies ups&downs, therapies / biotherapies - Immunodeficiencies & tolerance, Recap & questions
Annotation
Please note: the lectures are given in English language only.
Basic 1-semestral lecture course on immune system components and mechanisms. There is no qualification prerequisite. Suitable for students of biology, medicine, chemistry.
We are going to discuss basic theory of immune system functioning, including disease-related information in human pathologies and animal models in brief.
The course is targeted to students of 3rd (BSc.) and 4th (1st MSc.) year and PhD students in biomedical fields, incl. Medical faculty students as well as Erasmus students.