1. Introduction to toxicology. Definitions, branch differentiation.
2. Absorption, distribution and elimination of toxic substances.
3. The influence of chemical and physical factors on the organism and its functions.
4. Interaction of chemical and physical factors.
5. Analysis of toxic substances.
6. Risk assessment.
7. QSAR - prediction of the effects of toxic substances. References: Casarett and Douls´s Toxicology, 4th ed., M.O.Amdur, J.D.Doul, C.D.Klaassen, eds., Pergamon Press,
1991. General and Applied Toxicology, B.Ballantyne, T.Marrs, P.Turner, eds, Vol.I, II., M Stockton Press,
1993. Handbook on the Toxicology of Metals, Friberg, Nordberg, Vouk, eds., Vol.I, II., Elsevier,
1986.
Please note, the lectures are given in czech language only.
Specialized lecture on toxic substances and their effects on the living organisms. Facultative for all interested students of study program biology, chemistry and environmental protection.