Syllabus
LECTURES OF WINTER SEMESTER:
1. Protein stability - introduction
2. Proteasome
3. Ubiquitin ligase
4. Regulation of protein stability in the cell cycle
5. Regulation of protein stability in development
6. Protein degradation associated with ER
7. Autophagy - lysosome
8. Protein degradation in response to cytotoxic stress
9. Summary
Annotation
One-semester lecture course focused on deepening of knowledge about molecular mechanisms of protein dynamics and protein stability. The main aim of the course is to understand the proteasome-ubiquitin system and its function in the regulation of cell cycle, development, immune response, autophagy or protein quality control.