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Genomické metody

Předmět na Přírodovědecká fakulta |
MB151P129

Tento text není v aktuálním jazyce dostupný. Zobrazuje se verze "en".Sylabus

Topics covered:

- microarrays, next generation sequencing - how they work, technologies, applications, advantages, limitations

- analyses of genome, transcriptome (RNA-seq), translatome..., single-cell analyses

- epigenomics - chromatin modifications, transcription factor binding sites (ChIP-seq)

- analysis of 3D nuclear architecture - chromosome conformation capture methods (HiC)

- metagenomics - analysis of environmental samples, composition of microbial communities

- genetic interactions - mutant libraries, synthetic genetic array, siRNA screens, mapping the functional architecture of a cell

- chemical genetics - identification of novel targets for therapy

- tools for genomic data processing and analysis - Galaxy framework, genome browsers...

- visualizing genomic data

- integrating data from various methods

- databases for "omics" data  

Practical sessions will be based on online tools and resources (eg. Galaxy). No programming skill are needed.