Syllabus
1) History, interesting notes.
2) Stereochemistry, types of chirality, nomenclature.
3) Enantioseparation by gas chromatography.
4) Enantioseparation by high performance liquid chromatography.
5) Utilizing of electromigration methods for chiral separation.
6) Ways of study of stereoselective interactions.
7) Detectors, ways of detection, techniques for determination of optical purity and absolute configuration.
8) Analysis of drugs.
Annotation
The lecture deals with basic principles of enantioselective separations. Characteristics and properties of optical isomers.
Importance of chiral separation. Use of different separation systems.
Chiral selectors. Enantioselective separation methods - GC, HPLC, TLC and electromigration techniques.
Application of chiral separations in analyses of drugs food components, agrochemicals and other industrially important compounds. New development in the field.