Sylabus of the subject (modules of lectures which serves also as questions for postgraduate examination)

Modul I:- Polypharmacotherapy- causes, risk factors, prevalence on national and international level, negative outcomes

Modul II.- Geriatric syndromes I. - causes, risk factors, diagnostics, complications, relationship to polypharmacotherapy

Modul III.- Geriatric syndromes II. - causes, risk factors, diagnostics, complications, relationship to polypharmacotherapy

Modul IV.- Specific features of druh-related geriatric syndromes, geriatric drug-disease interactions

Modul V.- Theory of combined drug regimens and importance of pharmacokinetic (particularly metabolic) a farmacodynamic interactions for estimation of clinically-significant risks of pharmacotherapy

Modul VI. Specif features of low-dose drug regimens in the old age, importance for the management of polypharmacotherapy

Modul VII.- Prescribing cascades and other risk factors leading to multiple drug regimens- evidence from epidemiological studies

Modul VIII.-Classification systems and expert explicite criteria of potentially inappropriate medicatsions in the old age (PIMs)

Modul IX.- Important national and European initiatives and projects targeted to reduction of risky polypharmacotherapy in the old age

Modul X.- Ageing of the world population, prolongation of life-expectancy, phenomenon of risky polypharmacotherapy and possiblities of reduction of risky polypharmacotherapy