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polar metabolites
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Mgr. Kateřina Hrušková
External person at Faculty of Pharmacy in Hradec Králové
8 publications
Publications
publication
Hydrophilic interaction liquid chromatography in the separation of a moderately lipophilic drug from its highly polar metabolites - The cardioprotectant dexrazoxane as a model case
2011 |
Faculty of Pharmacy in Hradec Králové
publication
Structure-Activity Relationships of Nitro-Substituted Aroylhydrazone Iron Chelators with Antioxidant and Antiproliferative Activities
2018 |
Faculty of Pharmacy in Hradec Králové
publication
Aroylhydrazone iron chelators: Tuning antioxidant and antiproliferative properties by hydrazide modifications
2016 |
Faculty of Pharmacy in Hradec Králové
publication
Synthesis and analysis of novel analogues of dexrazoxane and its open-ring hydrolysis product for protection against anthracycline cardiotoxicity in vitro and in vivo
2015 |
Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové
publication
Structure-Activity Relationships of Novel Salicylaldehyde Isonicotinoyl Hydrazone (SIH) Analogs: Iron Chelation, Anti-Oxidant and Cytotoxic Properties
2014 |
Faculty of Pharmacy in Hradec Králové
publication
Methyl and ethyl ketone analogs of salicylaldehyde isonicotinoyl hydrazone: Novel iron chelators with selective antiproliferative action
2012 |
Faculty of Pharmacy in Hradec Králové
publication
Synthesis and initial in vitro evaluations of novel antioxidant aroylhydrazone iron chelators with increased stability against plasma hydrolysis
2011 |
Faculty of Pharmacy in Hradec Králové
publication
Comparison of various iron chelators used in clinical practice as protecting agents against catecholamine-induced oxidative injury and cardiotoxicity
2011 |
Faculty of Pharmacy in Hradec Králové
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