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CYP1A1/2
Person
Class
Person
Publication
Programmes
RNDr. Michaela Čermáková Ph.D.
Academic staff at Faculty of Science
2 classes
35 publications
Classes
class
Seminar for Bachelor Thesis
MC250S05 |
Faculty of Science
class
Seminar for Diploma Thesis
MC250S06 |
Faculty of Science
Publications
publication
Induction of cytochromes P450 1A1 and 1A2 suppresses formation of DNA adducts by carcinogenic aristolochic acid I in rats in vivo
2016 |
Faculty of Science
publication
Role of dihydromyricetin in cytochrome P450-mediated metabolism and carcinogen activation
2015 |
Faculty of Science, Faculty of Pharmacy in Hradec Králové
publication
The Anticancer Drug Ellipticine Activated with Cytochrome P450 Mediates DNA Damage Determining Its Pharmacological Efficiencies: Studies with Rats, Hepatic Cytochrome P450 Reductase Null (HRN (TM)) Mice and Pure Enzymes
2015 |
Faculty of Science
publication
The Anticancer Drug Ellipticine Induces Cytochromes P450 1A1, 1A2 and 3A, Cytochrome b(5) and NADPH:Cytochrome P450 Oxidoreductase in Rat Liver, Kidney and Lung
2013 |
Faculty of Science
publication
The effect of benzo[a]pyrene on metabolic activation of anticancer drug ellipticine in mice
2013 |
Faculty of Science
publication
Role of Cytochromes P450 1A1/2 in Detoxication and Activation of Carcinogenic Aristolochic Acid I: Studies with the Hepatic NADPH:Cytochrome P450 Reductase Null (HRN) Mouse Model
2011 |
Faculty of Science, First Faculty of Medicine, Faculty of Physical Education and Sport
publication
Cytochrome b(5) shifts oxidation of the anticancer drug ellipticine by cytochromes P450 1A1 and 1A2 from its detoxication to activation, thereby modulating its pharmacological efficacy
2011 |
Faculty of Science
publication
Application of hepatic cytochrome b(5)/P450 reductase null (HBRN) mice to study the role of cytochrome b(5) in the cytochrome P450-mediated bioactivation of the anticancer drug ellipticine
2019 |
Faculty of Science
publication
Cytochrome b(5) impacts on cytochrome P450-mediated metabolism of benzo[a]pyrene and its DNA adduct formation: studies in hepatic cytochrome b(5)/P450 reductase null (HBRN) mice
2018 |
Faculty of Science
publication
Modulation of xenobiotic conjugation enzymes by dihydromyricetin in rats
2017 |
Faculty of Science, Faculty of Pharmacy in Hradec Králové
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