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Cells
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MUDr. Tomáš Brtnický Ph.D.
Academic staff at Second Faculty of Medicine
25 publications
Publications
publication
An autologous dendritic cell vaccine promotes anticancer immunity in patients with ovarian cancer with low mutational burden and cold tumors
2022 |
First Faculty of Medicine, Second Faculty of Medicine, Third Faculty of Medicine, Faculty of Medicine in Hradec Králové, Central Library of Charles University
publication
Peripheral gene signatures reveal distinct cancer patient immunotypes with therapeutic implications for autologous DC-based vaccines
2022 |
First Faculty of Medicine, Second Faculty of Medicine, Third Faculty of Medicine, Faculty of Medicine in Hradec Králové
publication
M2-like macrophages dictate clinically relevant immunosuppression in metastatic ovarian cancer
2020 |
Second Faculty of Medicine, Third Faculty of Medicine, Faculty of Medicine in Hradec Králové
publication
Calreticulin exposure correlates with robust adaptive antitumor immunity and favorable prognosis in ovarian carcinoma patients
2019 |
Second Faculty of Medicine, Third Faculty of Medicine, Faculty of Medicine in Hradec Králové, Faculty of Medicine in Pilsen
publication
TIM-3 Dictates Functional Orientation of the Immune Infiltrate in Ovarian Cancer
2019 |
Second Faculty of Medicine, Third Faculty of Medicine, Faculty of Medicine in Hradec Králové
publication
Mature dendritic cells correlate with favorable immune infiltrate and improved prognosis in ovarian carcinoma patients
2018 |
Second Faculty of Medicine, Third Faculty of Medicine, Faculty of Medicine in Hradec Králové
publication
Expression of tumor antigens on primary ovarian cancer cells compared to established ovarian cancer cell lines
2016 |
Second Faculty of Medicine
publication
Clinical relevance of regulatory T cells monitoring in the peripheral blood of ovarian cancer patients
2015 |
First Faculty of Medicine, Faculty of Physical Education and Sport, Second Faculty of Medicine
publication
Dynamics of T-cell infiltration during the course of ovarian cancer: The gradual shift from a Th17 effector cell response to a predominant infiltration by regulatory T-cells
2013 |
First Faculty of Medicine, Faculty of Physical Education and Sport, Second Faculty of Medicine
publication
Active cellular immunotherapy of ovarian cancer using dendritic cells
2012 |
Second Faculty of Medicine
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