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in vivo toxicity
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PharmDr. Vendula Šepsová Ph.D.
External academic staff at Faculty of Pharmacy in Hradec Králové
29 publications
Publications
publication
Novel tacrine-tryptophan hybrids: Multi-target directed ligands as potential treatment for Alzheimer's disease
2019 |
Central Library of Charles University, Faculty of Medicine in Hradec Králové
publication
Development of small bisquaternary cholinesterase inhibitors as drugs for pre-treatment of nerve agent poisonings
2018 |
Publication without faculty affiliation
publication
Tacrine-Trolox Hybrids: A Novel Class of Centrally Active, Nonhepatotoxic Multi-Target-Directed Ligands Exerting Anticholinesterase and Antioxidant Activities with Low In Vivo Toxicity
2015 |
Publication without faculty affiliation
publication
Structure-Guided Design of N-Methylpropargylamino- Quinazoline Derivatives as Multipotent Agents for the Treatment of Alzheimer's Disease
2023 |
Faculty of Science, Faculty of Pharmacy in Hradec Králové
publication
Non-covalent acetylcholinesterase inhibitors: In vitro screening and molecular modeling for novel selective insecticides
2022 |
Publication without faculty affiliation
publication
Tacrine - Benzothiazoles: Novel class of potential multitarget anti-Alzheimer's drugs dealing with cholinergic, amyloid and mitochondrial systems
2021 |
Central Library of Charles University, Faculty of Medicine in Hradec Králové
publication
Huprine Y-Tryptophan heterodimers with potential implication to Alzheimer's disease treatment
2021 |
Faculty of Pharmacy in Hradec Králové, First Faculty of Medicine
publication
Tacrine and its 7-methoxy derivate; time-change concentration in plasma and brain tissue and basic toxicological profile in rats
2021 |
Faculty of Medicine in Hradec Králové
publication
Phenothiazine-Tacrine Heterodimers: Pursuing Multitarget Directed Approach in Alzheimer's Disease
2021 |
Publication without faculty affiliation
publication
Development of versatile and potent monoquaternary reactivators of acetylcholinesterase
2021 |
Publication without faculty affiliation
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