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toxicity
Person
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Person
Publication
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prof. MUDr. Zdeněk Kleibl Ph.D.
Academic staff at First Faculty of Medicine
1 class
2 study programmes
184 publications
Class
class
Selected chapters of biochemistry and pathobiochemistry
B90008 |
First Faculty of Medicine
Study programme
programme
Biochemistry and Pathobiochemistry
+1
🇨🇿 PhD. |
First Faculty of Medicine
Publications
publication
Contribution of the Beta-ureidopropionase (UPB1) gene alterations to the development of fluoropyrimidine-related toxicity
2012 |
First Faculty of Medicine
publication
Contribution of dihydropyrimidinase gene alterations to the development of serious toxicity in fluoropyrimidine-treated cancer patients.
2010 |
First Faculty of Medicine
publication
Lack of large intragenic rearrangements in dihydropyrimidine dehydrogenase (DPYD) gene in fluoropyrimidine-treated patients with high-grade toxicity.
2009 |
First Faculty of Medicine
publication
Influence of dihydropyrimidine dehydrogenase gene (DPYD) coding sequence variants on the development of fluoropyrimidine-related toxicity in patients with high-grade toxicity and patients with excellent tolerance of fluoropyrimidine-based chemotherapy
2009 |
First Faculty of Medicine
publication
Prediction of toxicity fluoropyrimids used in the treatment of cancer
2009 |
First Faculty of Medicine
publication
Project 'DPD online': the possibility of toxicity prediction of 5-fluorouracil and its derivates
2003 |
First Faculty of Medicine
publication
Low Frequency of Cancer-Predisposition Gene Mutations in Liver Transplant Candidates with Hepatocellular Carcinoma
2023 |
First Faculty of Medicine, Central Library of Charles University, Faculty of Science
publication
Germline multigene panel testing of patients with endometrial cancer
2023 |
First Faculty of Medicine, Faculty of Medicine in Pilsen, Faculty of Science
publication
Importance of Germline and Somatic Alterations in Human MRE11, RAD50, and NBN Genes Coding for MRN Complex
2023 |
First Faculty of Medicine, Faculty of Science
publication
ENIGMA CHEK2gether Project: A Comprehensive Study Identifies Functionally Impaired CHEK2 Germline Missense Variants Associated with Increased Breast Cancer Risk
2023 |
First Faculty of Medicine, Central Library of Charles University
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