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Lipinski's rules
Person
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Person
Publication
Programmes
PharmDr. Lucie Smutná Ph.D.
Academic staff at Faculty of Pharmacy in Hradec Králové
4 classes
17 publications
Classes
class
Principles of Dosimetry and Radiation Protection
+2
GAF214 |
Faculty of Pharmacy in Hradec Králové
class
Principles of Dosimetry and Radioation Protection
GB192 |
Faculty of Pharmacy in Hradec Králové
Publications
publication
Discovery of Novel Human Constitutive Androstane Receptor Agonists with the Imidazo[1,2-a]pyridine Structure
2023 |
Faculty of Pharmacy in Hradec Králové, First Faculty of Medicine, Central Library of Charles University
publication
2-Substituted quinazolines: Partial agonistic and antagonistic ligands of the constitutive androstane receptor (CAR)
2023 |
Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové
publication
Gene Expression Profiling of 1alpha,25(OH)2D3 Treatment in 2D/3D Human Hepatocyte Models Reveals CYP3A4 Induction but Minor Changes in Other Xenobiotic-Metabolizing Genes
2022 |
Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Pilsen
publication
Expression dynamics of pregnane X receptor-controlled genes in 3D primary human hepatocyte spheroids
2022 |
Faculty of Pharmacy in Hradec Králové
publication
Transcriptional and post-transcriptional regulation of the pregnane X receptor: a rationale for interindividual variability in drug metabolism
2021 |
Faculty of Pharmacy in Hradec Králové
publication
New total synthesis and structure confirmation of putative (+)-hyacinthacine C-3 and (+)-5-epi-hyacinthacine C-3
2021 |
Faculty of Pharmacy in Hradec Králové
publication
The 3'-untranslated region contributes to the pregnane X receptor (PXR) expression down-regulation by PXR ligands and up-regulation by glucocorticoids
2020 |
Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové
publication
Trans-resveratrol, but not other natural stilbenes occurring in food, carries the risk of drug-food interaction via inhibition of cytochrome P450 enzymes or interaction with xenosensor receptors
2019 |
Faculty of Pharmacy in Hradec Králové
publication
Teriflunomide Is an Indirect Human Constitutive Androstane Receptor (CAR) Activator Interacting With Epidermal Growth Factor (EGF) Signaling
2018 |
Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové
publication
Resveratrol modifies biliary secretion of cholephilic compounds in sham-operated and cholestatic rats
2017 |
Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové
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