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thiosemicarbazone
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prof. PharmDr. Milan Nobilis CSc.
Academic staff at Faculty of Pharmacy in Hradec Králové
110 publications
Publications
publication
LC-MS/MS identification of the principal in vitro and in vivo phase I metabolites of the novel thiosemicarbazone anti-cancer drug, Bp4eT
2012 |
Faculty of Pharmacy in Hradec Králové
publication
Gut microbiota metabolizes nabumetone in vitro: Consequences for its bioavailability in vivo in the rodents with altered gut microbiome
2019 |
Faculty of Pharmacy in Hradec Králové
publication
The Importance of Wireless Capsule Endoscopy for Research into the Intestin Absorption Window of 5-Aminosalicylic Acid in Experimental Pigs
2017 |
Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové
publication
In vitro metabolism of fenofibric acid by carbonyl reducing enzymes
2016 |
Faculty of Pharmacy in Hradec Králové
publication
Novel Derivatives of Benfluron and Dimefluron: Synthesis and Anticancer activity
2015 |
Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové
publication
Imaging and Evaluating Method as Part of Endoscopical Diagnostic Approaches
2014 |
Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové
publication
Simultaneous determination of the novel thiosemicarbazone anti-cancer agent, Bp4eT, and its main phase I metabolites in plasma: Application to a pilot pharmacokinetic study in rats
2014 |
Faculty of Pharmacy in Hradec Králové
publication
Identification of combined conjugation of nabumetone phase I metabolites with glucuronic acid and glycine in minipig biotransformation using coupling high-performance liquid chromatography with electrospray ionization mass spectrometry
2014 |
Faculty of Pharmacy in Hradec Králové
publication
Role of carbonyl reducing enzymes in the phase I biotransformation of the non-steroidal anti-inflammatory drug nabumetone in vitro
2013 |
Faculty of Pharmacy in Hradec Králové
publication
Analytical power of LLE-HPLC-PDA-MS/MS in drug metabolism studies: Identification of new nabumetone metabolites
2013 |
Faculty of Pharmacy in Hradec Králové
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