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RNDr. Karel Chalupský Ph.D.
External academic staff at First Faculty of Medicine, Faculty of Science, Faculty of Mathematics and Physics
35 publications
Publications
publication
Discovery of Novel Human Constitutive Androstane Receptor Agonists with the Imidazo[1,2-a]pyridine Structure
2023 |
First Faculty of Medicine, Central Library of Charles University, Faculty of Pharmacy in Hradec Králové
publication
Rational Design of Highly Potent SARS-CoV-2 nsp14 Methyltransferase Inhibitors
2023 |
Faculty of Science, Central Library of Charles University
publication
Design, Synthesis, Biological Evaluation, and Crystallographic Study of Novel Purine Nucleoside Phosphorylase Inhibitors
2023 |
Faculty of Science, Central Library of Charles University
publication
Off-target lipid metabolism disruption by the mouse constitutive androstane receptor ligand TCPOBOP in humanized mice
2022 |
First Faculty of Medicine, Central Library of Charles University, Faculty of Physical Education and Sport, Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové
publication
Simvastatin and Dehydroepiandrosterone Sulfate Effects Against Hypoxic Pulmonary Hypertension Are Not Additive
2022 |
Second Faculty of Medicine
publication
Discovery of Modified Amidate (ProTide) Prodrugs of Tenofovir with Enhanced Antiviral Properties
2021 |
Faculty of Science, Central Library of Charles University
publication
Localization of SARS-CoV-2 Capping Enzymes Revealed by an Antibody against the nsp10 Subunit
2021 |
Central Library of Charles University
publication
Pregestational diabetes increases fetoplacental vascular resistance in rats
2018 |
First Faculty of Medicine, Faculty of Physical Education and Sport, Second Faculty of Medicine
publication
MMP-19 deficiency causes aggravation of colitis due to defects in innate immune cell function
2016 |
Faculty of Science, Central Library of Charles University
publication
Diaphorase Can Metabolize Some Vasorelaxants to NO and Eliminate NO Scavenging Effect of 2-Phenyl-4,4,5,5,-tetramethylimidazoline-1-oxyl-3-oxide (PTIO)
2004 |
First Faculty of Medicine, Faculty of Mathematics and Physics
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