Publications
- Both Nitro Groups Are Essential for High Antitubercular Activity of 3,5-Dinitrobenzylsulfanyl Tetrazoles and 1,3,4-Oxadiazoles through the Deazaflavin-Dependent Nitroreductase Activation Pathway2024 | Faculty of Pharmacy in Hradec Králové
- Discovery of Novel Human Constitutive Androstane Receptor Agonists with the Imidazo[1,2-a]pyridine Structure2023 | Faculty of Pharmacy in Hradec Králové, First Faculty of Medicine, Central Library of Charles University
- 2-Substituted quinazolines: Partial agonistic and antagonistic ligands of the constitutive androstane receptor (CAR)2023 | Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové
- Carvedilol impairs bile acid homeostasis in mice: implication for nonalcoholic steatohepatitis2023 | Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové
- Gene Expression Profiling of 1alpha,25(OH)2D3 Treatment in 2D/3D Human Hepatocyte Models Reveals CYP3A4 Induction but Minor Changes in Other Xenobiotic-Metabolizing Genes2022 | Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Pilsen
- Real-time monitoring of Metridia luciferase release from cells upon interaction with model toxic substances by a fully automatic flow setup - A proof of concept2022 | Faculty of Pharmacy in Hradec Králové
- Diazepam Promotes Translocation of Human Constitutive Androstane Receptor (CAR) via Direct Interaction with the Ligand-Binding Domain2020 | Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové, Faculty of Physical Education and Sport
- The 3'-untranslated region contributes to the pregnane X receptor (PXR) expression down-regulation by PXR ligands and up-regulation by glucocorticoids2020 | Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové
- Stilbene compound trans-3,4,5,4'-tetramethoxystilbene, a potential anticancer drug, regulates constitutive androstane receptor (Car) target genes, but does not possess proliferative activity in mouse liver2019 | Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové
- Trans-resveratrol, but not other natural stilbenes occurring in food, carries the risk of drug-food interaction via inhibition of cytochrome P450 enzymes or interaction with xenosensor receptors2019 | Faculty of Pharmacy in Hradec Králové
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