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Metridia luciferase
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Mgr. Jan Dušek Ph.D.
Academic staff at Faculty of Pharmacy in Hradec Králové
15 publications
Publications
publication
Real-time monitoring of Metridia luciferase release from cells upon interaction with model toxic substances by a fully automatic flow setup - A proof of concept
2022 |
Faculty of Pharmacy in Hradec Králové
publication
Both Nitro Groups Are Essential for High Antitubercular Activity of 3,5-Dinitrobenzylsulfanyl Tetrazoles and 1,3,4-Oxadiazoles through the Deazaflavin-Dependent Nitroreductase Activation Pathway
2024 |
Faculty of Pharmacy in Hradec Králové
publication
Discovery of Novel Human Constitutive Androstane Receptor Agonists with the Imidazo[1,2-a]pyridine Structure
2023 |
Faculty of Pharmacy in Hradec Králové, First Faculty of Medicine, Central Library of Charles University
publication
2-Substituted quinazolines: Partial agonistic and antagonistic ligands of the constitutive androstane receptor (CAR)
2023 |
Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové
publication
Carvedilol impairs bile acid homeostasis in mice: implication for nonalcoholic steatohepatitis
2023 |
Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové
publication
Gene Expression Profiling of 1alpha,25(OH)2D3 Treatment in 2D/3D Human Hepatocyte Models Reveals CYP3A4 Induction but Minor Changes in Other Xenobiotic-Metabolizing Genes
2022 |
Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Pilsen
publication
Diazepam Promotes Translocation of Human Constitutive Androstane Receptor (CAR) via Direct Interaction with the Ligand-Binding Domain
2020 |
Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové, Faculty of Physical Education and Sport
publication
The 3'-untranslated region contributes to the pregnane X receptor (PXR) expression down-regulation by PXR ligands and up-regulation by glucocorticoids
2020 |
Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové
publication
Stilbene compound trans-3,4,5,4'-tetramethoxystilbene, a potential anticancer drug, regulates constitutive androstane receptor (Car) target genes, but does not possess proliferative activity in mouse liver
2019 |
Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové
publication
Trans-resveratrol, but not other natural stilbenes occurring in food, carries the risk of drug-food interaction via inhibition of cytochrome P450 enzymes or interaction with xenosensor receptors
2019 |
Faculty of Pharmacy in Hradec Králové
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