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Ing. Martin Drastík Ph.D.
Academic staff at Faculty of Pharmacy in Hradec Králové
10 publications
Publications
publication
Allosteric Antagonism of the Pregnane X Receptor (PXR): Current-State-of-the-Art and Prediction of Novel Allosteric Sites
2022 |
Faculty of Pharmacy in Hradec Králové
publication
(E)-7-Ethylidene-lithocholic Acid (7-ELCA) Is a Potent Dual Farnesoid X Receptor (FXR) Antagonist and GPBAR1 Agonist Inhibiting FXR-Induced Gene Expression in Hepatocytes and Stimulating Glucagon-like Peptide-1 Secretion From Enteroendocrine Cells
2021 |
Faculty of Pharmacy in Hradec Králové, Faculty of Science, Faculty of Medicine in Hradec Králové
publication
3 beta-Isoobeticholic acid efficiently activates the farnesoid X receptor (FXR) due to its epimerization to 3 alpha-epimer by hepatic metabolism
2020 |
Faculty of Pharmacy in Hradec Králové, Faculty of Science, Faculty of Medicine in Hradec Králové
publication
Diazepam Promotes Translocation of Human Constitutive Androstane Receptor (CAR) via Direct Interaction with the Ligand-Binding Domain
2020 |
Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové, Faculty of Physical Education and Sport
publication
Terbinafine-loaded branched PLGA-based cationic nanoparticles with modifiable properties
2019 |
Faculty of Pharmacy in Hradec Králové
publication
Mucoadhesive plasticized system of branched poly(lactic-co-glycolic acid) with aciclovir
2016 |
Faculty of Pharmacy in Hradec Králové
publication
Origin of heat-induced structural changes in dissolved organic matter
2013 |
Faculty of Pharmacy in Hradec Králové
publication
Selection of Plasticizer for Branched Oligoesters Used as Drug Carriers
2013 |
Faculty of Pharmacy in Hradec Králové
publication
Plasticized branched aliphatic oligoesters as potential mucoadhesive drug carriers
2013 |
Faculty of Pharmacy in Hradec Králové
publication
Branched polyesters as perspective drug carriers
Publication without faculty affiliation
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