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Anti-Novel
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PharmDr. Vít Šesták Ph.D.
External academic staff at Faculty of Pharmacy in Hradec Králové
17 publications
Publications
publication
UHPLC-HRMS study of pharmacokinetics of a novel hybrid cholinesterase inhibitor K1234: A comparison between in silico, in vitro and in vivo data
2022 |
Faculty of Medicine in Hradec Králové
publication
UHPLC-HRMS study of anti-Alzheimer's drug candidates: metabolism of 7-MEOTA-tryptophan hybrids hampers their passage into brain
2019 |
Faculty of Medicine in Hradec Králové
publication
Novel and potent anti-tumor and anti-metastatic di-2-pyridylketone thiosemicarbazones demonstrate marked differences in pharmacology between the first and second generation lead agents
2015 |
Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové
publication
In Vitro Characterization of the Pharmacological Properties of the Anti-Cancer Chelator, Bp4eT, and Its Phase I Metabolites
2015 |
Faculty of Pharmacy in Hradec Králové
publication
Simultaneous determination of the novel thiosemicarbazone anti-cancer agent, Bp4eT, and its main phase I metabolites in plasma: Application to a pilot pharmacokinetic study in rats
2014 |
Faculty of Pharmacy in Hradec Králové
publication
LC-MS/MS identification of the principal in vitro and in vivo phase I metabolites of the novel thiosemicarbazone anti-cancer drug, Bp4eT
2012 |
Faculty of Pharmacy in Hradec Králové
publication
The UHPLC-UV method applied for the forced degradation study of ixazomib and HRMS identification of its degradation products
2023 |
Faculty of Pharmacy in Hradec Králové
publication
Methaemoglobinaemia and oesophageal burns after accidental ingestion of an alkyl nitrite
2022 |
Faculty of Medicine in Hradec Králové, First Faculty of Medicine
publication
Improving Antimicrobial Activity and Physico-Chemical Properties by Isosteric Replacement of 2-Aminothiazole with 2-Aminooxazole
2022 |
Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové
publication
The Impact of Dextran Sodium Sulfate-Induced Gastrointestinal Injury on the Pharmacokinetic Parameters of Donepezil and Its Active Metabolite 6-O-desmethyldonepezil, and Gastric Myoelectric Activity in Experimental Pigs
2021 |
Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové
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