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enzyme induction
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prof. PharmDr. Petr Pávek Ph.D.
Academic staff at Faculty of Pharmacy in Hradec Králové
12 classes
194 publications
Classes
class
Personalized Pharmacotherapy and Pharmacogenetics
+1
GAF356 |
Faculty of Pharmacy in Hradec Králové
class
Introduction to Pharmacology and Toxicology
+1
GB174 |
Faculty of Pharmacy in Hradec Králové
class
Pharmacology and Toxicology
+1
GB180 |
Faculty of Pharmacy in Hradec Králové
class
Nutrigenomics
+3
GDEFGN02 |
Faculty of Pharmacy in Hradec Králové
class
Clinical Pharmacokinetics
+1
GDEKSF16 |
Faculty of Pharmacy in Hradec Králové
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Publications
publication
Investigation of Orlistat effects on PXR activation and CYP3A4 expression in primary human hepatocytes and human intestinal LS174T cells
2010 |
Central Library of Charles University
publication
Benzodiazepines medazepam and midazolam are activators of pregnane X receptor and weak inducers of CYP3A4: Investigation in primary cultures of human hepatocytes and hepatocarcinoma cell lines
2010 |
Central Library of Charles University
publication
Both Nitro Groups Are Essential for High Antitubercular Activity of 3,5-Dinitrobenzylsulfanyl Tetrazoles and 1,3,4-Oxadiazoles through the Deazaflavin-Dependent Nitroreductase Activation Pathway
2024 |
Faculty of Pharmacy in Hradec Králové
publication
Discovery of Novel Human Constitutive Androstane Receptor Agonists with the Imidazo[1,2-a]pyridine Structure
2023 |
Faculty of Pharmacy in Hradec Králové, Central Library of Charles University, First Faculty of Medicine
publication
2-Substituted quinazolines: Partial agonistic and antagonistic ligands of the constitutive androstane receptor (CAR)
2023 |
Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové
publication
Carvedilol impairs bile acid homeostasis in mice: implication for nonalcoholic steatohepatitis
2023 |
Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové
publication
When Two Become One: Conformational Changes in FXR/RXR Heterodimers Bound to Steroidal Antagonists
2023 |
Faculty of Pharmacy in Hradec Králové, Faculty of Science
publication
Dietary phytochemicals as modulators of human pregnane X receptor
2023 |
Faculty of Pharmacy in Hradec Králové
publication
Off-target lipid metabolism disruption by the mouse constitutive androstane receptor ligand TCPOBOP in humanized mice
2022 |
Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové, Central Library of Charles University, First Faculty of Medicine, Faculty of Physical Education and Sport
publication
Off-target lipid metabolism disruption by the mouse constitutive androstane receptor ligand TCPOBOP in humanized mice
2022 |
Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové, First Faculty of Medicine
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