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prof. MUDr. Pavel Klener Ph.D.
Academic staff at First Faculty of Medicine
112 publications
Publications
publication
Lenalidomide enhances antitumor functions of chimeric antigen receptor modified T cells
2016 |
First Faculty of Medicine
publication
Pevonedistat, a NEDD8-activating enzyme inhibitor, is active in mantle cell lymphoma and enhances rituximab activity in vivo
2016 |
First Faculty of Medicine
publication
The plant alkaloid and anti-leukemia drug homoharringtonine sensitizes resistant human colorectal carcinoma cells to TRAIL-induced apoptosis via multiple mechanisms
2013 |
Central Library of Charles University, First Faculty of Medicine
publication
Resistance to TRAIL in mantle cell lymphoma cells is associated with the decreased expression of purine metabolism enzymes
2013 |
First Faculty of Medicine
publication
The cultivation of human multipotent mesenchymal stromal cells in clinical grade medium for bone tissue engineering
2009 |
First Faculty of Medicine, Second Faculty of Medicine, Faculty of Medicine in Hradec Králové
publication
TRAIL-induced apoptosis of HL60 leukemia cells: two distinct phenotypes of acquired TRAIL resistance that are accompanied with resistance to TNF alpha but not to idarubicin and cytarabine
2009 |
First Faculty of Medicine
publication
Ibrutinib in mantle cell lymphoma: a real-world retrospective multi-center analysis of 77 patients treated in the Czech Republic
2023 |
First Faculty of Medicine, Faculty of Medicine in Hradec Králové, Third Faculty of Medicine
publication
mTOR inhibition amplifies the anti-lymphoma effect of PI3Kβ/δ blockage in diffuse large B-cell lymphoma
2023 |
First Faculty of Medicine, Third Faculty of Medicine
publication
Sequencing-based analysis of clonal evolution of 25 mantle cell lymphoma patients at diagnosis and after failure of standard immunochemotherapy
2023 |
First Faculty of Medicine, Second Faculty of Medicine
publication
Cell-specific modulation of mitochondrial respiration and metabolism by the pro-apoptotic Bcl-2 family members Bax and Bak
2023 |
First Faculty of Medicine, Faculty of Science
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