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steady state
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Person
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doc. Ing. Jaroslav Chládek Ph.D.
Academic staff at Faculty of Medicine in Hradec Králové
2 classes
240 publications
Classes
class
Modern Research Methods in Pharmacology
FG50035 |
Faculty of Medicine in Hradec Králové
class
Modern research methods in pharmacology
FV50049 |
Faculty of Medicine in Hradec Králové
Publications
publication
A Rat Model of Early Sepsis: Relationships between Gentamicin Pharmacokinetics and Systemic and Renal Effects of Bacterial Lipopolysaccharide Combined with Interleukin-2
2012 |
Faculty of Medicine in Hradec Králové, First Faculty of Medicine
publication
High-dose methotrexate in children with acute lymphoblastic leukemia: 7-hydroxymethotrexate systemic exposure and urinary concentrations at the steady state correlate well with those of methotrexate
2010 |
Faculty of Medicine in Hradec Králové
publication
Steady-state of azathioprine during initiation treatment of pediatric inflammatory bowel disease
2010 |
Faculty of Medicine in Hradec Králové
publication
Pharmacokinetics of azathioprine during the first weeks of treatment of Crohn´s disease and ulcerative colitis in children and adolescents
+1
2009 |
Faculty of Medicine in Hradec Králové
publication
A pilot study of pharmacokinetically guided dosing of oral methotrexate in the initial phase of psoriasis treatment
+1
2008 |
Faculty of Medicine in Hradec Králové
publication
Development of water-soluble prodrugs of the bisdioxopiperazine topoisomerase II beta inhibitor ICRF-193 as potential cardioprotective agents against anthracycline cardiotoxicity
2021 |
Faculty of Medicine in Hradec Králové, Faculty of Pharmacy in Hradec Králové
publication
Lung Collapse during Mini-Thoracotomy Reduces Penetration of Cefuroxime to the Tissue: Interstitial Microdialysis Study in Animal Models
2021 |
Faculty of Medicine in Hradec Králové
publication
Impact of cumulative fluid balance on the pharmacokinetics of extended infusion meropenem in critically ill patients with sepsis
2021 |
Faculty of Medicine in Hradec Králové
publication
Evaluation of Neutrophil Gelatinase-Associated Lipocalin as a Predictor of Glomerular Filtration Rate and Amikacin Clearance During Early Rat Endotoxemia: Comparison with Traditional Endogenous and Exogenous Biomarkers
2020 |
Faculty of Medicine in Hradec Králové, First Faculty of Medicine, Faculty of Pharmacy in Hradec Králové
publication
Plasmafiltration as an effective method in the removal of circulating pegylated liposomal doxorubicin (PLD) and the reduction of mucocutaneous toxicity during the treatment of advanced platinum-resistant ovarian cancer
2020 |
Faculty of Medicine in Hradec Králové
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